Cryogenic X-ray crystallographic studies of biomacromolecules at Turkish light source "Turkish DeLight"
buir.contributor.author | Çinal, Zeynep Sena | |
dc.citation.epage | 13 | en_US |
dc.citation.issueNumber | 1 | |
dc.citation.spage | 1 | |
dc.citation.volumeNumber | 47 | |
dc.contributor.author | Atalay, N. | |
dc.contributor.author | Akcan, E. K. | |
dc.contributor.author | Gül, M. | |
dc.contributor.author | Ayan, E. | |
dc.contributor.author | Destan, E. | |
dc.contributor.author | Ertem, F. B. | |
dc.contributor.author | Tokay, N. | |
dc.contributor.author | Çakılkaya, B. | |
dc.contributor.author | Nergiz, Z. | |
dc.contributor.author | Karakadıoğlu, G. | |
dc.contributor.author | Kepçeoğlu, A. | |
dc.contributor.author | Yapıcı, İ. | |
dc.contributor.author | Tosun, B. | |
dc.contributor.author | Baldır, N. | |
dc.contributor.author | Yıldırım, G. | |
dc.contributor.author | Johnson, J. A. | |
dc.contributor.author | Güven, Ö. | |
dc.contributor.author | Shafiei, A. | |
dc.contributor.author | Arslan, N. E. | |
dc.contributor.author | Yılmaz, M. | |
dc.contributor.author | Kulakman, C. | |
dc.contributor.author | Paydos, S. S. | |
dc.contributor.author | Çinal, Zeynep Sena | |
dc.contributor.author | Şabanoğlu, K. | |
dc.contributor.author | Pazarçeviren, A. | |
dc.contributor.author | Yılmaz, A. | |
dc.contributor.author | Canbay, B. | |
dc.contributor.author | Aşcı, B. | |
dc.contributor.author | Kartal, E. | |
dc.contributor.author | Tavlı, S. | |
dc.contributor.author | Çalıseki, M. | |
dc.contributor.author | Göç, G. | |
dc.contributor.author | Mermer, A. | |
dc.contributor.author | Yeşilay, G. | |
dc.contributor.author | Altuntaş, S. | |
dc.contributor.author | Tateishi, H. | |
dc.contributor.author | Otsuka, M. | |
dc.contributor.author | Fujita, M. | |
dc.contributor.author | Tekin, Ş. | |
dc.contributor.author | Çiftçi, H. | |
dc.contributor.author | Durdağı, S. | |
dc.contributor.author | Dinler Doğanay, G. | |
dc.contributor.author | Karaca, E. | |
dc.contributor.author | Kaplan Türköz, B. | |
dc.contributor.author | Kabasakal, B. V. | |
dc.contributor.author | Katı, A. | |
dc.contributor.author | Demirci, H. | |
dc.date.accessioned | 2024-03-14T07:57:44Z | |
dc.date.available | 2024-03-14T07:57:44Z | |
dc.date.issued | 2023-01-01 | |
dc.description.abstract | X-ray crystallography is a robust and powerful structural biology technique that provides high-resolution atomic structures of biomacromolecules. Scientists use this technique to unravel mechanistic and structural details of biological macromolecules (e.g., proteins, nucleic acids, protein complexes, protein-nucleic acid complexes, or large biological compartments). Since its inception, single-crystal cryocrystallography has never been performed in Türkiye due to the lack of a single-crystal X-ray diffractometer. The X-ray diffraction facility recently established at the University of Health Sciences, İstanbul, Türkiye will enable Turkish and international researchers to easily perform high-resolution structural analysis of biomacromolecules from single crystals. Here, we describe the technical and practical outlook of a state-of-the-art home-source X-ray, using lysozyme as a model protein. The methods and practice described in this article can be applied to any biological sample for structural studies. Therefore, this article will be a valuable practical guide from sample preparation to data analysis. | |
dc.description.provenance | Made available in DSpace on 2024-03-14T07:57:44Z (GMT). No. of bitstreams: 1 Cryogenic_X-ray_crystallographic_studies_of_biomacromolecules_at_Turkish_light_source_Turkish_DeLight.pdf: 2170093 bytes, checksum: 9b00f637ec612955876cfd28e9bbe510 (MD5) Previous issue date: 2023-01-01 | en |
dc.identifier.doi | 10.55730/1300-0152.2637 | |
dc.identifier.eissn | 1303-6092 | |
dc.identifier.issn | 13000152 | |
dc.identifier.uri | https://hdl.handle.net/11693/114722 | |
dc.language.iso | en | |
dc.publisher | TÜBİTAK | |
dc.relation.isversionof | https://dx.doi.org/10.55730/1300-0152.2637 | |
dc.source.title | Turkish Journal of Biology | |
dc.subject | X-ray crystallography | |
dc.subject | Light source | |
dc.subject | Structural biology | |
dc.subject | Atomic resolution | |
dc.subject | Drug repurposing | |
dc.subject | Drug development | |
dc.subject | Structural dynamics | |
dc.title | Cryogenic X-ray crystallographic studies of biomacromolecules at Turkish light source "Turkish DeLight" | |
dc.type | Article |
Files
Original bundle
1 - 1 of 1
Loading...
- Name:
- Cryogenic_X-ray_crystallographic_studies_of_biomacromolecules_at_Turkish_light_source_Turkish_DeLight.pdf
- Size:
- 2.07 MB
- Format:
- Adobe Portable Document Format
License bundle
1 - 1 of 1
No Thumbnail Available
- Name:
- license.txt
- Size:
- 2.01 KB
- Format:
- Item-specific license agreed upon to submission
- Description: