Dynamic resource scheduling of biomanufacturing projects

Available
The embargo period has ended, and this item is now available.

Date

2020-05

Editor(s)

Advisor

Supervisor

Co-Advisor

Co-Supervisor

Instructor

BUIR Usage Stats
2
views
10
downloads

Citation Stats

Series

Abstract

We consider the scheduling problem for biomanufacturing projects that involve multiple tasks and “no-wait” constraints between some of these tasks. The aim is to create schedules that ensure timely delivery of products while enabling schedule revisions to accommodate additional constraints realized during the execution of these projects. We formulate the problem as a mixed-integer linear programming model with the objective of minimizing total tardiness, and propose a dynamic scheduling approach that solves a series of modified mixed-integer linear programming models to revise and improve the schedule. We conduct numerical studies to investigate the performance of this approach and compare its performance to a traditional proactive scheduling approach. In collaboration with biomanufacturing companies, we create a scheduling tool and validate the approach with implementation in an industry setting.

Source Title

Computers and Industrial Engineering

Publisher

Elsevier

Course

Other identifiers

Book Title

Degree Discipline

Degree Level

Degree Name

Citation

Published Version (Please cite this version)

Language

English