Role of lipooligosaccharide in the attachment of Moraxella catarrhalis to human pharyngeal epithelial cells
Date
2005
Authors
Akgul, G.
Erturk, A.
Turkoz, M.
Turan, T.
Ichinose, A.
Nagatake, T.
Ahmed, K.
Editor(s)
Advisor
Supervisor
Co-Advisor
Co-Supervisor
Instructor
Source Title
Microbiology and Immunology
Print ISSN
0385-5600
Electronic ISSN
Publisher
Wiley
Volume
49
Issue
10
Pages
931 - 935
Language
English
Type
Journal Title
Journal ISSN
Volume Title
Series
Abstract
The goal of this study was to determine the role of lipooligosaccharide in the attachment of Moraxella catarrhalis to human pharyngeal epithelial cells. Strain 2951 and its Pk mutant strain 2951 galE were used in this study. This study suggests that the Pk epitope of LOS is not an adhesin for M. catarrhalis, but plays a crucial role by its surface charge in the initial stage of attachment.