Role of FLT3 and its potential interaction partner, Hsp27 in hepatocellular carcinoma

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dc.citation.issueNumberSupplement 2en_US
dc.citation.spage107en_US
dc.citation.volumeNumber56en_US
dc.contributor.authorAydın, Muammer Merveen_US
dc.contributor.authorBayın, N. S.en_US
dc.contributor.authorAkhan, Eceen_US
dc.contributor.authorCan, A.en_US
dc.contributor.authorAkçalı, Kamil Canen_US
dc.coverage.spatialBarselona, Spainen_US
dc.date.accessioned2019-07-12T06:52:15Z
dc.date.available2019-07-12T06:52:15Z
dc.date.issued2012-04en_US
dc.departmentDepartment of Molecular Biology and Geneticsen_US
dc.descriptionConference Name: 47th Annual Meeting of the European Association for the Study of the Liver, EASL 2012en_US
dc.descriptionDate of Conference: 18-22 April 2012en_US
dc.description.abstractRegeneration ability of liver is known to be associated with the activation of resident oval cells. Previously our group showed that oval cell marker, FLT3 changes its cellular localization in response to partial hepatectomy and suggested a role in liver regeneration. In addition, FLT3 was shown to play an important role in cellular proliferation and activation of PI3K and Ras. Hsp27 on the other hand, is a small chaperone that has roles in the inhibition of apoptosis and overexpressed in a wide range of cancers increasing their metastatic potential. Due to the role of FLT3 in liver regeneration and cellular proliferation, we aimed to analyze the effect of FLT3 in hepatocellular carcinoma (HCC) both in vitro and in vivo and its interaction with Hsp27.en_US
dc.description.provenanceSubmitted by Zeynep Aykut (zeynepay@bilkent.edu.tr) on 2019-07-12T06:52:15Z No. of bitstreams: 1 Role_of_FLT3_and_its_potential_interaction_partner_ Hsp27_in_hepatocellular_carcinoma.pdf: 57770 bytes, checksum: 99fc0b998af14883ac3a9704425b2228 (MD5)en
dc.description.provenanceMade available in DSpace on 2019-07-12T06:52:15Z (GMT). No. of bitstreams: 1 Role_of_FLT3_and_its_potential_interaction_partner_ Hsp27_in_hepatocellular_carcinoma.pdf: 57770 bytes, checksum: 99fc0b998af14883ac3a9704425b2228 (MD5) Previous issue date: 2012-04en
dc.identifier.doi10.1016/S0168-8278(12)60267-0en_US
dc.identifier.issn0168-8278
dc.identifier.urihttp://hdl.handle.net/11693/52250
dc.language.isoEnglishen_US
dc.publisherElsevieren_US
dc.relation.isversionofhttps://doi.org/10.1016/S0168-8278(12)60267-0en_US
dc.source.titleJournal of Hepatologyen_US
dc.source.titleAbstracts of the International Liver Congress 2012: 47th Annual Meeting of the European Association for the Study of the Liveren_US
dc.titleRole of FLT3 and its potential interaction partner, Hsp27 in hepatocellular carcinomaen_US
dc.typeArticleen_US

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