Intravascular MR-monitored balloon angioplasty: An in vivo feasibility study

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dc.citation.epage959en_US
dc.citation.issueNumber6en_US
dc.citation.spage953en_US
dc.citation.volumeNumber9en_US
dc.contributor.authorYang, Xiaomingen_US
dc.contributor.authorBolster Jr., B. D.en_US
dc.contributor.authorKraitchman, D. L.en_US
dc.contributor.authorAtalar, Erginen_US
dc.date.accessioned2016-02-08T10:42:34Z
dc.date.available2016-02-08T10:42:34Z
dc.date.issued1998en_US
dc.departmentDepartment of Electrical and Electronics Engineeringen_US
dc.description.abstractPURPOSE: To develop a new method for monitoring balloon angioplasty by using an intravascular magnetic resonance (MR) imaging technique. MATERIALS AND METHODS: Nine New Zealand White rabbits were used: seven for technique refinement, including surgery, device insertion, stenosis creation, and MR protocol development; and two for the final MR imaging of the balloon angioplasty. The in vivo experimental method involved insertion of a catheter antenna and a balloon catheter, via femoral arteriotomies bilaterally, into the target site of the upper abdominal aorta, where a stenosis was artificially created by binding a plastic cable tie. Then, the entire process of the dilation of the stenosis with balloon inflation was monitored under MR fluoroscopy. RESULTS: Catheter insertions were successful, and a 5-mm-long stenosis of the aorta was produced in all nine rabbits. Eight complete balloon angioplasty procedures were satisfactorily monitored and recorded, showing clearly the stenosis of the aorta at the beginning of the procedure, the dilation of the stenosis during the balloon inflation, and the complete opening of the stenosis after balloon dilation. CONCLUSION: Preliminary results of in vivo balloon angioplasty monitored with intravascular MR imaging are presented. MR fluoroscopy, based on the intravascular MR imaging technique, may represent a potential alternative to x-ray fluoroscopy for guiding interventional treatment of cardiovascular diseases.en_US
dc.description.provenanceMade available in DSpace on 2016-02-08T10:42:34Z (GMT). No. of bitstreams: 1 bilkent-research-paper.pdf: 70227 bytes, checksum: 26e812c6f5156f83f0e77b261a471b5a (MD5) Previous issue date: 1998en
dc.identifier.doi10.1016/S1051-0443(98)70429-4
dc.identifier.issn1051-0443en_US
dc.identifier.urihttp://hdl.handle.net/11693/25306en_US
dc.language.isoEnglishen_US
dc.publisherElsevier Inc.en_US
dc.relation.isversionofhttps://doi.org/10.1016/S1051-0443(98)70429-4en_US
dc.source.titleJournal of Vascular and Interventional Radiologyen_US
dc.subjectMagnetic resonance (MR), intravascularen_US
dc.subjectGadodiamideen_US
dc.subjectGadolinium pentetateen_US
dc.subjectAbdominal aortaen_US
dc.subjectAnimal experimenten_US
dc.subjectAorta stenosisen_US
dc.subjectBalloon catheteren_US
dc.subjectBalloon dilatationen_US
dc.subjectContrast enhancementen_US
dc.subjectImage analysisen_US
dc.subjectInterventional radiologyen_US
dc.subjectNuclear magnetic resonance imagingen_US
dc.subjectPercutaneous transluminal angioplastyen_US
dc.subjectFluoroscopyen_US
dc.subjectGadolinium DTPAen_US
dc.titleIntravascular MR-monitored balloon angioplasty: An in vivo feasibility studyen_US
dc.typeArticleen_US

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