Spectrally selective imaging with wideband balanced steady-state free precession MRI

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buir.contributor.authorÇukur, Tolga
dc.citation.epage1141en_US
dc.citation.issueNumber3en_US
dc.citation.spage1132en_US
dc.citation.volumeNumber75en_US
dc.contributor.authorÇukur, Tolgaen_US
dc.date.accessioned2018-04-12T10:58:22Z
dc.date.available2018-04-12T10:58:22Z
dc.date.issued2016en_US
dc.departmentDepartment of Electrical and Electronics Engineeringen_US
dc.departmentNational Magnetic Resonance Research Center (UMRAM)en_US
dc.departmentAysel Sabuncu Brain Research Center (BAM)en_US
dc.description.abstractPurpose Unwanted, bright fat signals in balanced steady-state free precession sequences are commonly suppressed using spectral shaping. Here, a new spectral-shaping method is proposed to significantly improve the uniformity of stopband suppression without compromising the level of passband signals. Methods The proposed method combines binomial-pattern excitation pulses with a wideband balanced steady-state free precession sequence kernel. It thereby increases the frequency separation between the centers of pass and stopbands by π radians, enabling improved water-fat contrast. Simulations were performed to find the optimal flip angles and subpulse spacing for the binomial pulses that maximize contrast and signal efficiency. Results Comparisons with a conventional binomial balanced steady-state free precession sequence were performed in simulations as well as phantom and in vivo experiments at 1.5 T and 3 T. Enhanced fat suppression is demonstrated in vivo with an average improvement of 58% in blood-fat and 68% in muscle-fat contrast (P < 0.001, Wilcoxon signed-rank test). Conclusion The proposed binomial wideband balanced steady-state free precession method is a promising candidate for spectrally selective imaging with enhanced reliability against field inhomogeneities.en_US
dc.identifier.doi10.1002/mrm.25700en_US
dc.identifier.issn0740-3194
dc.identifier.urihttp://hdl.handle.net/11693/36956
dc.language.isoEnglishen_US
dc.publisherJohn Wiley and Sons Inc.en_US
dc.relation.isversionofhttp://dx.doi.org/10.1002/mrm.25700en_US
dc.source.titleMagnetic Resonance in Medicineen_US
dc.subjectSteady-state free precessionen_US
dc.subjectSpectralen_US
dc.subjectSelectivityen_US
dc.subjectRF pulseen_US
dc.subjectExcitationen_US
dc.subjectFat suppressionen_US
dc.subjectWidebanden_US
dc.titleSpectrally selective imaging with wideband balanced steady-state free precession MRIen_US
dc.typeArticleen_US

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Department of Electrical and Electronics Engineering
Aysel Sabuncu Brain Research Center (BAM)
National Magnetic Resonance Research Center (UMRAM)