Evaluation of psychosocial functioning in the acute treatment term of major depressive disorder: A 16-week multi-centered follow-up study

Simple item page
buir.contributor.authorAltunsoy, Neslihan
dc.citation.epage102883-5en_US
dc.citation.spage102883-1en_US
dc.citation.volumeNumber66en_US
dc.contributor.authorAltunsoy, Neslihan
dc.contributor.authorDikici, D. S.
dc.contributor.authorÇökmüş, F. P.
dc.contributor.authorÖzkan, H. M.
dc.contributor.authorAşçıbaşı, K.
dc.contributor.authorAlçı, D.
dc.contributor.authorKuru, E.
dc.contributor.authorAydemir, Ö.
dc.date.accessioned2022-01-26T10:54:18Z
dc.date.available2022-01-26T10:54:18Z
dc.date.issued2021-12
dc.departmentDepartment of Psychologyen_US
dc.description.abstractMajor depressive disorder is the leading cause of non-fatal burden, and disability in adulthood. Even though depression is well-treated in the acute term,psychosocial functioning does not get back to the premorbid level most of the time. In this present study, it is aimed to evaluate the outcome of the acute term treatment of major depressive disorder in terms of psychosocial functioning. Methods: The study is an open-label, observational, multi-center follow-up study for four months of patients with major depressive disorder according to DSM-5. Patients were evaluated with Montgomery Asberg Depression Rating Scale (MADRS), Sheehan Disability Scale (SDS) and Short Form-36 (SF-36) at the beginning, and at the 2., 4., 8., 12. and 16.weeks. Results: 100 patients were invited to the study and 56 patients completed the study.As a result of the treatment, the mean MADRS and SDS scores decreased significantly. All domains of SF-36 were improved significantly with the treatment. Unfortunately patients suffering from MDD could not reach the normative data,especially on the domains of social functioning, role emotional, pain, and general health perception. Treatment outcomes show that SNRI users presented higher scores on the domains of pain and physical functioning. However SSRI users showed better outcomes on the domains of mental health and vitality. Conclusion: Our research corroborated that even patients gain symptomatic remission in MDD treatment, psy-chosocial dysfunction persists. It is also concluded that different antidepressant options may act differently on treatment outcomes.en_US
dc.embargo.release2022-12-31
dc.identifier.doi10.1016/j.ajp.2021.102883en_US
dc.identifier.eissn1876-2026
dc.identifier.issn1876-2018
dc.identifier.urihttp://hdl.handle.net/11693/76796
dc.language.isoEnglishen_US
dc.publisherElsevier BVen_US
dc.relation.isversionofhttps://doi.org/10.1016/j.ajp.2021.102883en_US
dc.source.titleAsian Journal of Psychiatryen_US
dc.subjectAntidepressive agentsen_US
dc.subjectDepressionen_US
dc.subjectDepressive disorderen_US
dc.subjectPsychosocial functioningen_US
dc.subjectQuality of lifeen_US
dc.titleEvaluation of psychosocial functioning in the acute treatment term of major depressive disorder: A 16-week multi-centered follow-up studyen_US
dc.typeArticleen_US

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Evaluation_of_psychosocial_functioning_in_the_acute_treatment_term_of_major_depressive_disorder._A_16_week_multi-centered_follow-up_study.pdf
Size:
391.94 KB
Format:
Adobe Portable Document Format
Description:
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.69 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

Department of Psychology