Seroreactivity against PTEN-induced putative kinase 1 (PINK1) in Turkish patients with Behçet's disease

Date

2009

Authors

Vural, B.
Demirkan, A.
Ugurel, E.
Kalaylioglu-Wheeler, Z.
Esen, B. A.
Gure, A. O.
Gül, A.
Ozbek, U.

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Abstract

Background. Behçet’s disease (BD) is a multisystem inflammatory disorder characterized by recurrent oral ulcers, genital ulcers and ocular inflammation, as well as skin, joint, vascular, pulmonary, central nervous system (CNS) and gastrointestinal tract manifestations. The etiopathogenesis of BD has not yet been identified; but it has generally been accepted that several environmental factors may induce an inflammatory attack in genetically susceptible individuals. In this study, we aimed to identify antigens that could elicit high-titer IgG responses by the serological analysis of recombinant expression of cDNA libraries method (SEREX).

Source Title

Clinical and Experimental Rheumatology

Publisher

Pacini Editore SpA

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Citation

Published Version (Please cite this version)

Language

English