The systems biology graphical notation

Simple item page
buir.contributor.authorDemir, Emek
buir.contributor.authorDoğrusöz, Uğur
dc.citation.epage741en_US
dc.citation.issueNumber8en_US
dc.citation.spage735en_US
dc.citation.volumeNumber27en_US
dc.contributor.authorLe Novère, N.en_US
dc.contributor.authorHucka, M.en_US
dc.contributor.authorMi, H.en_US
dc.contributor.authorMoodie, S.en_US
dc.contributor.authorSchreiber, F.en_US
dc.contributor.authorSorokin, A.en_US
dc.contributor.authorDemir, Emeken_US
dc.contributor.authorWegner, K.en_US
dc.contributor.authorAladjem, M. I.en_US
dc.contributor.authorWimalaratne, S. M.en_US
dc.contributor.authorBergman, F. T.en_US
dc.contributor.authorGauges, R.en_US
dc.contributor.authorGhazal, P.en_US
dc.contributor.authorKawaji, H.en_US
dc.contributor.authorLi, L.en_US
dc.contributor.authorMatsuoka, Y.en_US
dc.contributor.authorVilléger, A.en_US
dc.contributor.authorBoyd, S. E.en_US
dc.contributor.authorCalzone, L.en_US
dc.contributor.authorCourtot, M.en_US
dc.contributor.authorDoğrusöz, Uğuren_US
dc.contributor.authorFreeman, T. C.en_US
dc.contributor.authorFunahashi, A.en_US
dc.contributor.authorGhosh, S.en_US
dc.contributor.authorJouraku, A.en_US
dc.contributor.authorKim, S.en_US
dc.contributor.authorKolpakov, F.en_US
dc.contributor.authorLuna, A.en_US
dc.contributor.authorSahle, S.en_US
dc.contributor.authorSchmidt, E.en_US
dc.contributor.authorWatterson, S.en_US
dc.contributor.authorWu, G.en_US
dc.contributor.authorGoryanin, I.en_US
dc.contributor.authorKell, D. B.en_US
dc.contributor.authorSander, C.en_US
dc.contributor.authorSauro, H.en_US
dc.contributor.authorSnoep, J. L.en_US
dc.contributor.authorKohn, K.en_US
dc.contributor.authorKitano, H.en_US
dc.date.accessioned2018-04-12T13:49:04Z
dc.date.available2018-04-12T13:49:04Z
dc.date.issued2009-08en_US
dc.departmentDepartment of Computer Engineeringen_US
dc.departmentBilkent Center for Bioinformatics (BCBI)
dc.description.abstractCircuit diagrams and Unified Modeling Language diagrams are just two examples of standard visual languages that help accelerate work by promoting regularity, removing ambiguity and enabling software tool support for communication of complex information. Ironically, despite having one of the highest ratios of graphical to textual information, biology still lacks standard graphical notations. The recent deluge of biological knowledge makes addressing this deficit a pressing concern. Toward this goal, we present the Systems Biology Graphical Notation (SBGN), a visual language developed by a community of biochemists, modelers and computer scientists. SBGN consists of three complementary languages: process diagram, entity relationship diagram and activity flow diagram. Together they enable scientists to represent networks of biochemical interactions in a standard, unambiguous way. We believe that SBGN will foster efficient and accurate representation, visualization, storage, exchange and reuse of information on all kinds of biological knowledge, from gene regulation, to metabolism, to cellular signaling. © 2009 Nature America, Inc.en_US
dc.identifier.doi10.1038/nbt.1558en_US
dc.identifier.eissn1546-1696
dc.identifier.issn1087-0156
dc.identifier.urihttp://hdl.handle.net/11693/38162
dc.language.isoEnglishen_US
dc.publisherNature Publishing Groupen_US
dc.relation.isversionofhttp://dx.doi.org/10.1038/nbt.1558en_US
dc.source.titleNature Biotechnologyen_US
dc.subjectActivity flowen_US
dc.subjectBiochemical interactionsen_US
dc.subjectCellular signalingen_US
dc.subjectCircuit diagramsen_US
dc.subjectComplex informationen_US
dc.subjectComputer scientistsen_US
dc.subjectEntity relationship diagramsen_US
dc.subjectGene regulationsen_US
dc.subjectGraphical notationen_US
dc.subjectProcess diagramen_US
dc.subjectSoftware toolen_US
dc.subjectSystems biologyen_US
dc.subjectTextual informationen_US
dc.subjectUnified modeling language diagramsen_US
dc.subjectVisual languageen_US
dc.subjectBiologyen_US
dc.subjectKnowledge representationen_US
dc.subjectLinguisticsen_US
dc.subjectQuery languagesen_US
dc.subjectStandardsen_US
dc.subjectUnified modeling languageen_US
dc.subjectAccuracyen_US
dc.subjectComputer programen_US
dc.subjectGene controlen_US
dc.subjectInformation processingen_US
dc.subjectLanguageen_US
dc.subjectMetabolic regulationen_US
dc.subjectMolecular biologyen_US
dc.subjectPriority journalen_US
dc.subjectSignal transductionen_US
dc.subjectComputer graphicsen_US
dc.subjectInterneten_US
dc.subjectSoftwareen_US
dc.titleThe systems biology graphical notationen_US
dc.typeArticleen_US

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
The_systems_biology_graphical_notation.pdf
Size:
1017.83 KB
Format:
Adobe Portable Document Format
Description:
Download

Collections

Department of Computer Engineering
Bilkent Center for Bioinformatics (BCBI)