Inter-varietal structural variation in grapevine genomes

Date
2016
Authors
Cardone, M. F.
D'Addabbo, P.
Alkan C.
Bergamini, C.
Catacchio, C. R.
Anaclerio, F.
Chiatante, G.
Marra, A.
Giannuzzi, G.
Perniola, R.
Editor(s)
Advisor
Supervisor
Co-Advisor
Co-Supervisor
Instructor
Source Title
Plant journal
Print ISSN
0960-7412
Electronic ISSN
Publisher
Wiley-Blackwell Publishing Ltd.
Volume
88
Issue
4
Pages
648 - 661
Language
English
Journal Title
Journal ISSN
Volume Title
Series
Abstract

Grapevine (Vitis vinifera L.) is one of the world's most important crop plants, which is of large economic value for fruit and wine production. There is much interest in identifying genomic variations and their functional effects on inter-varietal, phenotypic differences. Using an approach developed for the analysis of human and mammalian genomes, which combines high-throughput sequencing, array comparative genomic hybridization, fluorescent in�situ hybridization and quantitative PCR, we created an inter-varietal atlas of structural variations and single nucleotide variants (SNVs) for the grapevine genome analyzing four economically and genetically relevant table grapevine varieties. We found 4.8 million SNVs and detected 8% of the grapevine genome to be affected by genomic variations. We identified more than 700 copy number variation (CNV) regions and more than 2000 genes subjected to CNV as potential candidates for phenotypic differences between varieties

Course
Other identifiers
Book Title
Citation
Published Version (Please cite this version)