Rapid TAURUS for relaxation-based color magnetic particle imaging

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buir.contributor.authorAslan, M. Tunç
buir.contributor.authorÖzaslan, A. Alper
buir.contributor.authorSaritas, Emine Ulku
buir.contributor.orcidÖzaslan, A. Alper|0000-0003-4067-2904
buir.contributor.orcidSaritas, Emine Ulku|0000-0001-8551-1077
dc.citation.epage3786en_US
dc.citation.issueNumber12en_US
dc.citation.spage3774en_US
dc.citation.volumeNumber41en_US
dc.contributor.authorAslan, M. Tunç
dc.contributor.authorÖzaslan, A. Alper
dc.contributor.authorKurt, S.
dc.contributor.authorMuslu, Y.
dc.contributor.authorSaritas, Emine Ulku
dc.date.accessioned2023-02-16T07:32:05Z
dc.date.available2023-02-16T07:32:05Z
dc.date.issued2022-08-03
dc.departmentDepartment of Electrical and Electronics Engineeringen_US
dc.departmentNational Magnetic Resonance Research Center (UMRAM)en_US
dc.description.abstractMagnetic particle imaging (MPI) is a rapidly developing medical imaging modality that exploits the non-linear response of magnetic nanoparticles (MNPs). Color MPI widens the functionality of MPI, empowering it with the capability to distinguish different MNPs and/or MNP environments. The system function approach for color MPI relies on extensive calibrations that capture the differences in the harmonic responses of the MNPs. An alternative calibration-free x-space-based method called TAURUS estimates a map of the relaxation time constant, τ , by recovering the underlying mirror symmetry in the MPI signal. However, TAURUS requires a back and forth scanning of a given region, restricting its usage to slow trajectories with constant or piecewise constant focus fields (FFs). In this work, we propose a novel technique to increase the performance of TAURUS and enable τ map estimation for rapid and multi-dimensional trajectories. The proposed technique is based on correcting the distortions on mirror symmetry induced by time-varying FFs. We demonstrate via simulations and experiments in our in-house MPI scanner that the proposed method successfully estimates high-fidelity τ maps for rapid trajectories that provide orders of magnitude reduction in scanning time (over 300 fold for simulations and over 8 fold for experiments) while preserving the calibration-free property of TAURUS.en_US
dc.description.provenanceSubmitted by Fatma Kaya (fattttoky.55@gmail.com) on 2023-02-16T07:32:05Z No. of bitstreams: 1 Rapid_TAURUS_for_relaxation-based_color_magnetic_particle_İmaging.pdf: 2339603 bytes, checksum: 9daa036cb9701a21fbe85e4f620c47ea (MD5)en
dc.description.provenanceMade available in DSpace on 2023-02-16T07:32:05Z (GMT). No. of bitstreams: 1 Rapid_TAURUS_for_relaxation-based_color_magnetic_particle_İmaging.pdf: 2339603 bytes, checksum: 9daa036cb9701a21fbe85e4f620c47ea (MD5) Previous issue date: 2022-08-03en
dc.identifier.doi10.1109/TMI.2022.3195694en_US
dc.identifier.eissn1558-254X
dc.identifier.issn0278-0062
dc.identifier.urihttp://hdl.handle.net/11693/111395
dc.language.isoEnglishen_US
dc.publisherInstitute of Electrical and Electronics Engineers Inc.en_US
dc.relation.isversionofhttps://www.doi.org/10.1109/TMI.2022.3195694en_US
dc.source.titleIEEE Transactions on Medical Imagingen_US
dc.subjectMagnetic particle imagingen_US
dc.subjectColor MPIen_US
dc.subjectNanoparticle relaxationen_US
dc.subjectMirror symmetryen_US
dc.subjectX-space MPIen_US
dc.subjectRapid trajectoryen_US
dc.titleRapid TAURUS for relaxation-based color magnetic particle imagingen_US
dc.typeArticleen_US

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