The BioPAX community standard for pathway data sharing
buir.contributor.author | Demir, Emek | |
buir.contributor.author | Babur, Özgün | |
buir.contributor.author | Doğrusöz, Uğur | |
dc.citation.epage | 942 | en_US |
dc.citation.issueNumber | 9 | en_US |
dc.citation.spage | 935 | en_US |
dc.citation.volumeNumber | 28 | en_US |
dc.contributor.author | Demir, Emek | en_US |
dc.contributor.author | Cary, M. P. | en_US |
dc.contributor.author | Paley, S. | en_US |
dc.contributor.author | Fukuda, K. | en_US |
dc.contributor.author | Lemer, C. | en_US |
dc.contributor.author | Vastrik, I. | en_US |
dc.contributor.author | Wu, G. | en_US |
dc.contributor.author | D'Eustachio, P. | en_US |
dc.contributor.author | Schaefer, C. | en_US |
dc.contributor.author | Luciano, J. | en_US |
dc.contributor.author | Schacherer, F. | en_US |
dc.contributor.author | Martinez-Flores, I. | en_US |
dc.contributor.author | Hu, Z. | en_US |
dc.contributor.author | Jimenez-Jacinto, V. | en_US |
dc.contributor.author | Joshi-Tope, G. | en_US |
dc.contributor.author | Kandasamy, K. | en_US |
dc.contributor.author | Lopez-Fuentes, A. C. | en_US |
dc.contributor.author | Mi, H. | en_US |
dc.contributor.author | Pichler, E. | en_US |
dc.contributor.author | Rodchenkov, I. | en_US |
dc.contributor.author | Splendiani, A. | en_US |
dc.contributor.author | Tkachev, S. | en_US |
dc.contributor.author | Zucker, J. | en_US |
dc.contributor.author | Gopinath, G. | en_US |
dc.contributor.author | Rajasimha, H. | en_US |
dc.contributor.author | Ramakrishnan, R. | en_US |
dc.contributor.author | Shah, I. | en_US |
dc.contributor.author | Syed, M. | en_US |
dc.contributor.author | Anwar, N. | en_US |
dc.contributor.author | Babur, Özgün | en_US |
dc.contributor.author | Blinov, M. | en_US |
dc.contributor.author | Brauner, E. | en_US |
dc.contributor.author | Corwin, D. | en_US |
dc.contributor.author | Donaldson, S. | en_US |
dc.contributor.author | Gibbons, F. | en_US |
dc.contributor.author | Goldberg, R. | en_US |
dc.contributor.author | Hornbeck, P. | en_US |
dc.contributor.author | Luna, A. | en_US |
dc.contributor.author | Murray-Rust, P. | en_US |
dc.contributor.author | Neumann, E. | en_US |
dc.contributor.author | Reubenacker, O. | en_US |
dc.contributor.author | Samwald, M. | en_US |
dc.contributor.author | Iersel, Martijn van | en_US |
dc.contributor.author | Wimalaratne, S. | en_US |
dc.contributor.author | Allen, K. | en_US |
dc.contributor.author | Braun, B. | en_US |
dc.contributor.author | Whirl-Carrillo, M. | en_US |
dc.contributor.author | Cheung, Kei-Hoi | en_US |
dc.contributor.author | Dahlquist, K. | en_US |
dc.contributor.author | Finney, A. | en_US |
dc.contributor.author | Gillespie, M. | en_US |
dc.contributor.author | Glass, E. | en_US |
dc.contributor.author | Gong, L. | en_US |
dc.contributor.author | Haw, R. | en_US |
dc.contributor.author | Honig, M. | en_US |
dc.contributor.author | Hubaut, O. | en_US |
dc.contributor.author | Kane, D. | en_US |
dc.contributor.author | Krupa, S. | en_US |
dc.contributor.author | Kutmon, M. | en_US |
dc.contributor.author | Leonard, J. | en_US |
dc.contributor.author | Marks, D. | en_US |
dc.contributor.author | Merberg, D. | en_US |
dc.contributor.author | Petri, V. | en_US |
dc.contributor.author | Pico, A. | en_US |
dc.contributor.author | Ravenscroft, D. | en_US |
dc.contributor.author | Ren, L. | en_US |
dc.contributor.author | Shah, N. | en_US |
dc.contributor.author | Sunshine, M. | en_US |
dc.contributor.author | Tang R. | en_US |
dc.contributor.author | Whaley, R. | en_US |
dc.contributor.author | Letovksy, S. | en_US |
dc.contributor.author | Buetow, K. H. | en_US |
dc.contributor.author | Rzhetsky, A. | en_US |
dc.contributor.author | Schachter, V. | en_US |
dc.contributor.author | Sobral, B. S. | en_US |
dc.contributor.author | Doğrusöz, Uğur | en_US |
dc.contributor.author | McWeeney, S. | en_US |
dc.contributor.author | Aladjem, M. | en_US |
dc.contributor.author | Birney, E. | en_US |
dc.contributor.author | Collado-Vides, J. | en_US |
dc.contributor.author | Goto, S. | en_US |
dc.contributor.author | Hucka, M. | en_US |
dc.contributor.author | Novère, Nicolas Le | en_US |
dc.contributor.author | Maltsev, N. | en_US |
dc.contributor.author | Pandey, A. | en_US |
dc.contributor.author | Thomas, P. | en_US |
dc.contributor.author | Wingender, E. | en_US |
dc.contributor.author | Karp, P. D. | en_US |
dc.contributor.author | Sander, C. | en_US |
dc.contributor.author | Bader, G. D. | en_US |
dc.date.accessioned | 2018-04-12T13:49:34Z | |
dc.date.available | 2018-04-12T13:49:34Z | |
dc.date.issued | 2010-09 | en_US |
dc.department | Department of Computer Engineering | en_US |
dc.department | Bilkent Center for Bioinformatics (BCBI) | |
dc.description.abstract | Biological Pathway Exchange (BioPAX) is a standard language to represent biological pathways at the molecular and cellular level and to facilitate the exchange of pathway data. The rapid growth of the volume of pathway data has spurred the development of databases and computational tools to aid interpretation; however, use of these data is hampered by the current fragmentation of pathway information across many databases with incompatible formats. BioPAX, which was created through a community process, solves this problem by making pathway data substantially easier to collect, index, interpret and share. BioPAX can represent metabolic and signaling pathways, molecular and genetic interactions and gene regulation networks. Using BioPAX, millions of interactions, organized into thousands of pathways, from many organisms are available from a growing number of databases. This large amount of pathway data in a computable form will support visualization, analysis and biological discovery. © 2010 Nature America, Inc. All rights reserved. | en_US |
dc.description.provenance | Made available in DSpace on 2018-04-12T13:49:34Z (GMT). No. of bitstreams: 1 bilkent-research-paper.pdf: 179475 bytes, checksum: ea0bedeb05ac9ccfb983c327e155f0c2 (MD5) Previous issue date: 2010 | en |
dc.identifier.doi | 10.1038/nbt.1666 | en_US |
dc.identifier.issn | 1087-0156 | en_US |
dc.identifier.uri | http://hdl.handle.net/11693/38163 | en_US |
dc.language.iso | English | en_US |
dc.publisher | Nature Publishing Group | en_US |
dc.relation.isversionof | http://dx.doi.org/10.1038/nbt.1666 | en_US |
dc.source.title | Nature Biotechnology | en_US |
dc.subject | Biological discoveries | en_US |
dc.subject | Biological pathways | en_US |
dc.subject | Cellular levels | en_US |
dc.subject | Community standards | en_US |
dc.subject | Computational tools | en_US |
dc.subject | Data sharing | en_US |
dc.subject | Gene regulation network | en_US |
dc.subject | Genetic interaction | en_US |
dc.subject | Rapid growth | en_US |
dc.subject | Signaling pathways | en_US |
dc.subject | Database systems | en_US |
dc.subject | Visualization | en_US |
dc.subject | Data visualization | en_US |
dc.subject | Messenger RNA | en_US |
dc.subject | Protein kinase B | en_US |
dc.subject | Biological pathway exchange | en_US |
dc.subject | Copy number variation | en_US |
dc.subject | Database | en_US |
dc.subject | Enzyme substrate | en_US |
dc.subject | Fragmentation reaction | en_US |
dc.subject | Metabolism | en_US |
dc.subject | Molecular biology | en_US |
dc.subject | Molecular dynamics | en_US |
dc.subject | Molecular evolution | en_US |
dc.subject | Molecular interaction | en_US |
dc.subject | Priority journal | en_US |
dc.subject | Promoter region | en_US |
dc.subject | Protein DNA interaction | en_US |
dc.subject | Protein expression | en_US |
dc.subject | Protein modification | en_US |
dc.subject | Protein protein interaction | en_US |
dc.subject | Protein structure | en_US |
dc.subject | Review | en_US |
dc.subject | Semantics | en_US |
dc.subject | Single nucleotide polymorphism | en_US |
dc.subject | Structure analysis | en_US |
dc.subject | Computational biology | en_US |
dc.subject | Databases as topic | en_US |
dc.subject | Information dissemination | en_US |
dc.subject | Metabolic networks and pathways | en_US |
dc.subject | Programming languages | en_US |
dc.subject | Signal transduction | en_US |
dc.subject | Software | en_US |
dc.title | The BioPAX community standard for pathway data sharing | en_US |
dc.type | Article | en_US |
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