Linearity and shift invariance for quantitative magnetic particle imaging

buir.contributor.authorSarıtaş, Emine U.
dc.citation.epage1575en_US
dc.citation.issueNumber9en_US
dc.citation.spage1565en_US
dc.citation.volumeNumber32en_US
dc.contributor.authorLu, K.en_US
dc.contributor.authorGoodwill, P.en_US
dc.contributor.authorSarıtaş, Emine U.en_US
dc.contributor.authorZheng, B.en_US
dc.contributor.authorConolly, S.en_US
dc.date.accessioned2020-04-09T17:33:18Z
dc.date.available2020-04-09T17:33:18Z
dc.date.issued2013
dc.departmentAysel Sabuncu Brain Research Center (BAM)en_US
dc.description.abstractMagnetic Particle Imaging (MPI) is a promising tracer imaging modality that employs a kidney-safe contrast agent and does not use ionizing radiation. MPI already shows high contrast and sensitivity in small animal imaging, with great potential for many clinical applications, including angiography, cancer detection, inflammation imaging, and treatment monitoring. Currently, almost all clinically relevant imaging techniques can be modeled as systems with linearity and shift invariance (LSI), characteristics crucial for quantification and diagnostic utility. In theory, MPI has been proven to be LSI. However, in practice, high-pass filters designed to remove unavoidable direct feedthrough interference also remove information crucial to ensuring LSI in MPI scans. In this work, we present a complete theoretical and experimental description of the image artifacts from filtering. We then propose and validate a robust algorithm to completely restore the lost information for the x-space MPI method. We provide the theoretical, simulated, and experimental proof that our algorithm indeed restores the LSI properties of MPI.en_US
dc.description.provenanceSubmitted by Onur Emek (onur.emek@bilkent.edu.tr) on 2020-04-09T17:33:18Z No. of bitstreams: 1 Bilkent-research-paper.pdf: 268963 bytes, checksum: ad2e3a30c8172b573b9662390ed2d3cf (MD5)en
dc.description.provenanceMade available in DSpace on 2020-04-09T17:33:18Z (GMT). No. of bitstreams: 1 Bilkent-research-paper.pdf: 268963 bytes, checksum: ad2e3a30c8172b573b9662390ed2d3cf (MD5) Previous issue date: 2013en
dc.identifier.doi10.1109/TMI.2013.2257177en_US
dc.identifier.issn0278-0062
dc.identifier.urihttp://hdl.handle.net/11693/53578
dc.language.isoEnglishen_US
dc.publisherIEEEen_US
dc.relation.isversionofhttps://doi.org/10.1109/TMI.2013.2257177en_US
dc.source.titleIEEE Transactions on Medical Imagingen_US
dc.titleLinearity and shift invariance for quantitative magnetic particle imagingen_US
dc.typeArticleen_US

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