Analysis of a gene regulatory network model with time delay using the secant condition

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buir.contributor.authorÖzbay, Hitay
dc.citation.epage8en_US
dc.citation.issueNumber2en_US
dc.citation.spage5en_US
dc.citation.volumeNumber2en_US
dc.contributor.authorAhsen, M. E.en_US
dc.contributor.authorÖzbay, Hitayen_US
dc.contributor.authorNicolescu, Silviu-Iulianen_US
dc.date.accessioned2019-01-28T09:57:29Z
dc.date.available2019-01-28T09:57:29Z
dc.date.issued2016-10-04en_US
dc.departmentDepartment of Electrical and Electronics Engineeringen_US
dc.description.abstractA cyclic model for gene regulatory networks with time delayed negative feedback is analyzed using an extension of the so-called secant condition, which is originally developed for systems without time delays. It is shown that suf cient conditions obtained earlier for delay-independent local stability can be further improved for homogenous networks to obtain delay-dependent necessary and suf cient conditions, which are expressed in terms of the parameters of the Hill-type nonlinearity.en_US
dc.description.provenanceSubmitted by Dilek Doğanoğlu (doral@bilkent.edu.tr) on 2019-01-28T09:57:29Z No. of bitstreams: 1 Analysis-of-a-gene-regulatory-network-model.pdf: 969603 bytes, checksum: 7193a6d8b54792905a24d96267682216 (MD5)en
dc.description.provenanceMade available in DSpace on 2019-01-28T09:57:29Z (GMT). No. of bitstreams: 1 Analysis-of-a-gene-regulatory-network-model.pdf: 969603 bytes, checksum: 7193a6d8b54792905a24d96267682216 (MD5) Previous issue date: 2016-10-04en
dc.identifier.doi10.1109/LLS.2016.2615091en_US
dc.identifier.issn2332-7685
dc.identifier.urihttp://hdl.handle.net/11693/48412
dc.language.isoEnglishen_US
dc.publisherIEEEen_US
dc.relation.isversionofhttps://doi.org/10.1109/LLS.2016.2615091en_US
dc.source.titleIEEE Life Sciences Lettersen_US
dc.subjectGene regulatory networks (GRNs)en_US
dc.subjectLocal stabilityen_US
dc.subjectNegative feedbacken_US
dc.subjectSecant conditionen_US
dc.subjectTime delay systemsen_US
dc.titleAnalysis of a gene regulatory network model with time delay using the secant conditionen_US
dc.typeArticleen_US

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