Host variations in SARS-CoV-2 infection

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buir.contributor.authorÇetin, Güneysu
buir.contributor.orcidÇetin, Güneysu|0000-0002-3464-8695
dc.citation.epage424en_US
dc.citation.spage404en_US
dc.contributor.authorSavcı, E. Z.
dc.contributor.authorÖzkara, B.
dc.contributor.authorAlkan, K.
dc.contributor.authorNamdar, D. S.
dc.contributor.authorTunçer, G.
dc.contributor.authorKılınç, B. R.
dc.contributor.authorSuiçmez, E.
dc.contributor.authorÜnal, S.
dc.contributor.authorDönmüş, B.
dc.contributor.authorKaragülleoğlu, Z. Y.
dc.contributor.authorUncuoğlu, D. B.
dc.contributor.authorTekeli, C.
dc.contributor.authorMendi, A. H.
dc.contributor.authorBengi, V. U.
dc.contributor.authorSeval, G. C.
dc.contributor.authorKılıç, P.
dc.contributor.authorAltuntaş, E. G.
dc.contributor.authorDora, D. D.
dc.contributor.authorÇetin, Güneysu
dc.contributor.authorAltıok, D.
dc.date.accessioned2022-02-10T12:54:13Z
dc.date.available2022-02-10T12:54:13Z
dc.date.issued2021-08-30
dc.departmentDepartment of Molecular Biology and Geneticsen_US
dc.description.abstractThe novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the zoonotic pathogen that causes the “Coronavirus Disease of 2019 (COVID-19)”, and COVID-19 itself is yet to be thoroughly understood. Both the disease as well as the mechanisms by which the host interacts with the SARS-CoV-2 have not been fully enlightened. The epidemiological factors –e.g. age, sex, race-, the polymorphisms of the host proteins, the blood types and individual differences have all been in discussions about affecting the progression and the course of COVID-19 both individually and collectively, as their effects are mostly interwoven. We focused mainly on the effect of polymorphic variants of the host proteins that have been shown to take part in and/or affect the pathogenesis of COVID-19. Additionally, how the procedures of diagnosing and treating COVID-19 are affected by these variants and what possible changes can be implemented are the other questions, which are sought to be answered.en_US
dc.identifier.doi10.3906/biy-2104-67en_US
dc.identifier.eissn1303-6092
dc.identifier.issn1300-0152
dc.identifier.urihttp://hdl.handle.net/11693/77241
dc.language.isoEnglishen_US
dc.publisherTÜBİTAKen_US
dc.relation.isversionofhttps://doi.org/10.3906/biy-2104-67en_US
dc.source.titleTurkish Journal of Biologyen_US
dc.subjectAngiotensin-converting enzyme 2 (ACE2)en_US
dc.subjectTransmembrane serine protease 2 (tmprss2)en_US
dc.subjectHost geneticsen_US
dc.subjectPolymorphismsen_US
dc.subjectSars-cov-2en_US
dc.subjectToll-like receptors (tlr)en_US
dc.titleHost variations in SARS-CoV-2 infectionen_US
dc.typeReviewen_US

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