Targeted vessel reconstruction in non-contrast-enhanced steady-state free precession angiography

dc.citation.epage544en_US
dc.citation.issueNumber5en_US
dc.citation.spage532en_US
dc.citation.volumeNumber29en_US
dc.contributor.authorIlicak, E.en_US
dc.contributor.authorCetin S.en_US
dc.contributor.authorBulut E.en_US
dc.contributor.authorOguz, K. K.en_US
dc.contributor.authorSaritas, E. U.en_US
dc.contributor.authorUnal, G.en_US
dc.contributor.authorÇukur, T.en_US
dc.date.accessioned2018-04-12T10:58:20Z
dc.date.available2018-04-12T10:58:20Z
dc.date.issued2016en_US
dc.departmentDepartment of Electrical and Electronics Engineeringen_US
dc.departmentNational Magnetic Resonance Research Center (UMRAM)en_US
dc.description.abstractImage quality in non-contrast-enhanced (NCE) angiograms is often limited by scan time constraints. An effective solution is to undersample angiographic acquisitions and to recover vessel images with penalized reconstructions. However, conventional methods leverage penalty terms with uniform spatial weighting, which typically yield insufficient suppression of aliasing interference and suboptimal blood/background contrast. Here we propose a two-stage strategy where a tractographic segmentation is employed to auto-extract vasculature maps from undersampled data. These maps are then used to incur spatially adaptive sparsity penalties on vascular and background regions. In vivo steady-state free precession angiograms were acquired in the hand, lower leg and foot. Compared with regular non-adaptive compressed sensing (CS) reconstructions (CSlow), the proposed strategy improves blood/background contrast by 71.3±28.9% in the hand (mean±s.d. across acceleration factors 1-8), 30.6±11.3% in the lower leg and 28.1±7.0% in the foot (signed-rank test, P< 0.05 at each acceleration). The proposed targeted reconstruction can relax trade-offs between image contrast, resolution and scan efficiency without compromising vessel depiction.en_US
dc.description.provenanceMade available in DSpace on 2018-04-12T10:58:20Z (GMT). No. of bitstreams: 1 bilkent-research-paper.pdf: 179475 bytes, checksum: ea0bedeb05ac9ccfb983c327e155f0c2 (MD5) Previous issue date: 2016en
dc.identifier.doi10.1002/nbm.3497en_US
dc.identifier.issn0952-3480
dc.identifier.urihttp://hdl.handle.net/11693/36954
dc.language.isoEnglishen_US
dc.publisherJohn Wiley and Sons Ltden_US
dc.relation.isversionofhttp://dx.doi.org/10.1002/nbm.3497en_US
dc.source.titleNMR in Biomedicineen_US
dc.subjectAngiographyen_US
dc.subjectCompressed sensingen_US
dc.subjectRegularizationen_US
dc.subjectSegmentationen_US
dc.subjectSparsityen_US
dc.subjectVasculatureen_US
dc.titleTargeted vessel reconstruction in non-contrast-enhanced steady-state free precession angiographyen_US
dc.typeArticleen_US

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