A global effort to define the human genetics of protective immunity to SARS-CoV-2 infection
Date
2020
Editor(s)
Advisor
Supervisor
Co-Advisor
Co-Supervisor
Instructor
Source Title
Cell
Print ISSN
0092-8674
Electronic ISSN
Publisher
Elsevier
Volume
181
Issue
6
Pages
1194 - 1199
Language
English
Type
Journal Title
Journal ISSN
Volume Title
Series
Abstract
SARS-CoV-2 infection displays immense inter-individual clinical variability, ranging from silent infection to lethal disease. The role of human genetics in determining clinical response to the virus remains unclear. Studies of outliers—individuals remaining uninfected despite viral exposure and healthy young patients with life-threatening disease—present a unique opportunity to reveal human genetic determinants of infection and disease.