Browsing by Subject "Single molecule"
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Item Open Access Thinking outside the silicon box: molecular and logic as an additional layer of selectivity in singlet oxygen generation for photodynamic therapy(2009) Ozlem, S.; Akkaya, E. U.A simple derivative of a well-known dye bodipy appears to be a satisfactory sensitizer for singlet oxygen. Moreover, the rate of singlet oxygen generation can be modulated by two cancer-related cellular parameters, sodium ion concentration and acidity. Singlet oxygen generation rate is maximal when sodium ions and an organic acid were added. The operation of this molecular automaton follows AND logic, which introduces an additional layer of selectivity in the photodynamic action of the reagent. It should also be noted that in this system sensing, computing and actuating functions are realized within a single molecule. Copyright © 2008 American Chemical Society.Item Open Access Ultrasensitive label-free microcavity biosensors with high selectivity(IEEE, 2011) Özgür, Erol; Bayındır, Mehmet; Aktaş, OzanHigh quality factor whispering gallery mode microresonators have been recently shown to exhibit detection sensitivity of single molecule; however, the selectivity of these sensors among different types of analytes remains as an important issue, obscuring the broad applicability of optical microcavities. We demonstrate a surface modification strategy for fabrication of high selectivity and sensitivity microcavity biosensors in this study. © 2011 IEEE.