Browsing by Subject "Reference Values"
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Item Open Access Effect of six weeks aerobic training upon blood trace metals levels(2006) Savaş, S.; Şenel, Ö.; Çelikkan, H.; Uǧraş, A.; Aksu, M. L.This study was carried out to investigate the effects of 6-week aerobic exercise program upon blood Zn and Cu levels. There were 12 male university students with an average age of 21.67+/-0.89 years and no regular training habits participated in the study. The participants were subjected three days a week 1 hour a day continuous running program on treadmill with an intensity of 60-70% for a period of six weeks. They were fed with zinc and copper free diet throughout the study and it was made sure that they were not using copper or zinc containing vitamin tablets. The difference between the pre and post study period were found to be statistically significant as regards to both resting and maximal loading conditions (p<0.01). The pre and post training maxVO2 values were also found to be positively correlated with the copper and zinc levels in blood. Both the copper and zinc blood levels were found decreased after the training period p<0.05.Item Open Access Extreme clonality in lymphoblastoid cell lines with implications for allele specific expression analyses(2008) Plagnol V.; Uz, E.; Wallace, C.; Stevens H.; Clayton, D.; Ozcelik, T.; Todd J.A.Lymphoblastoid cell lines (LCL) are being actively and extensively used to examine the expression of specific genes and (genome-wide expression profiles, including allele specific expression assays. However, it has recently been shown that approximately 10% of human genes exhibit random patterns of monoallelic expression within single clones of LCLs. Consequently allelic imbalance studies could be significantly compromised if bulk populations of donor cells are clonal, or near clonal. Here, using X chromosome inactivation as a readout, we confirm and quantify widespread near monoclonality in two independent sets of cell lines. Consequently, we recommend where possible the use of bulk, non cell line, ex vivo cells for allele specific expression assays. © 2008 Plagnol et al.Item Open Access Reliability and validity of the Turkish version of the automatic thoughts questionnaire(Wiley, 1992) Sahin, N. H.; Sahin, N.The present study investigated the reliability and validity of the ATQ in the Turkish cultural context. It is hoped that with this type of cross- cultural information, the universality of the proposed cognitive constructs can be advocated more reliably. The subjects were 345 university students; the split-half reliability of the ATQ was found to be r = .91 and Cronbach's alpha was .93; and item/total correlations ranged between .36 and .69. The Turkish ATQ correlated well with the BDI (r = .75), and it discriminated successfully between the symptomatic and asymptomatic groups. Factor analysis revealed five factors that were similar to those found in American samples. Nevertheless, some differences were noticed in the relative strength of the factors and in the distribution of items into factor clusters.