Browsing by Subject "Particle manipulation"

Now showing 1 - 3 of 3

Open Access
3D modeling of on-chip acoustophoretic particle manipulation in a polymer microfluidic device
(Chemical and Biological Microsystems Society, 2016) Çaǧatay, E.; Özer, M. B.; Çetin, Barbaros
This study focuses on understanding of the sensitivities of the acoustophoretic process on uncertainties/errors in the geometric properties of the chip material and the piezoelectric actuators. The sensitivity of the acoustophoretic process is investigated both numerically and experimentally. For the numerical simulations a three dimensional finite element model is used. In the experimental analysis, a microfluidic chip with two stations is used. The first station has the accurate geometric values of the design and the second station has the introduced error in a geometric parameter so that the effect of this error can be demonstrated on the same chip and the channel.
Open Access
Dielectrophoresis in microfluidics technology
(2011) Çetin B.; Li, D.
Dielectrophoresis (DEP) is the movement of a particle in a non-uniform electric field due to the interaction of the particle's dipole and spatial gradient of the electric field. DEP is a subtle solution to manipulate particles and cells at microscale due to its favorable scaling for the reduced size of the system. DEP has been utilized for many applications in microfluidic systems. In this review, a detailed analysis of the modeling of DEP-based manipulation of the particles is provided, and the recent applications regarding the particle manipulation in microfluidic systems (mainly the published works between 2007 and 2010) are presented. © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Open Access
Investigation of effect of design and operating parameters on acoustophoretic particle separation via 3D device-level simulations
(Springer, 2020) Şahin, M. A.; Çetin, Barbaros; Özer, M. B.
In the present study, a 3D device-level numerical model is implemented via finite element method to assess the effects of design and operating parameters on the separation performance of a microscale acoustofluidic device. Elastodynamic equations together with electromechanical coupling at the piezoelectric actuators for the stress field within the solid parts, Helmholtz equation for the acoustic field within fluid, and Navier–Stokes equations for the fluid flow are coupled for the simulations. Once the zero-acoustic and flow fields are obtained, the trajectories of the particles are obtained by employing point–particle approach. The particle trajectories are simulated for many particles with different sizes released from random initial locations. Separation performances of the different cases are evaluated based on described metrics such as purity, yield, percentage of particle stuck in the channel, the force acting on the particles, residence time and separation parameter.