Browsing by Subject "Miniature instruments"

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Open Access
Femtosecond laser fabrication of fiber based optofluidic platform for flow cytometry applications
(SPIE, 2017) Serhatlioglu, Murat; Elbuken, Çağlar; Ortac, Bülend; Solmaz, Mehmet E.
Miniaturized optofluidic platforms play an important role in bio-analysis, detection and diagnostic applications. The advantages of such miniaturized devices are extremely low sample requirement, low cost development and rapid analysis capabilities. Fused silica is advantageous for optofluidic systems due to properties such as being chemically inert, mechanically stable, and optically transparent to a wide spectrum of light. As a three dimensional manufacturing method, femtosecond laser scanning followed by chemical etching shows great potential to fabricate glass based optofluidic chips. In this study, we demonstrate fabrication of all-fiber based, optofluidic flow cytometer in fused silica glass by femtosecond laser machining. 3D particle focusing was achieved through a straightforward planar chip design with two separately fabricated fused silica glass slides thermally bonded together. Bioparticles in a fluid stream encounter with optical interrogation region specifically designed to allocate 405nm single mode fiber laser source and two multi-mode collection fibers for forward scattering (FSC) and side scattering (SSC) signals detection. Detected signal data collected with oscilloscope and post processed with MATLAB script file. We were able to count number of events over 4000events/sec, and achieve size distribution for 5.95μm monodisperse polystyrene beads using FSC and SSC signals. Our platform shows promise for optical and fluidic miniaturization of flow cytometry systems. © 2017 SPIE.
Open Access
Miniaturization and characterization of metamaterial resonant particles
(IEEE, 2008-10) Aznar, F.; Bonache, J.; Martín, F.; Özbay, Ekmel; Alıcı, K. Boratay; Bilotti, F.; Tricarico, S.; Vegni, L.; Baena, J. D.; Jelinek, L.; Marqués, R.
This paper is focussed on the miniaturization and characterization of semi-lumped resonators, of interest for the synthesis of metamaterial-based structures such as metamaterial transmission lines, frequency selective surfaces, absorbers, and radiating elements, among others. The particles consist on metallic patterns etched on a dielectric and are inspired on the split ring resonator, SRR (that is, the formerly resonant particle used for the synthesis of left handed metamaterials). The different strategies for miniaturization are discussed and examples are given. It is shown that by using two metallic levels connected through vias it is possible to achieve very small electrical size for the particles (namely, below λ/100, where λ is the wavelength in the considered substrate at resonance). A method to determine the electrical parameters of the resonators in metamaterial transmission line configurations is also presented, and the possibility to determine the characteristics of the isolated particles is discussed. Finally, examples of application of this technique are presented. This work is of interest for the synthesis of effective media metamaterials based on resonant elements. © 2008 EuMA.