Browsing by Subject "Injection molding"
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Item Open Access Fabrication of polymer micro needles for transdermal drug delivery system using DLP based projection stereo-lithography(Elsevier, 2016) Ali, Z.; Türeyen, E. Buğra; Karpat, Yiğit; Çakmakcı, MelihFabrication of micro needles, which reduce pain during insertion and lessen tissue injury, has recently attracted great interest. Different manufacturing systems have been utilized for the advancement of micro needles such as two-photon photo polymerization, bulk lithography, droplet-borne air blowing and injection molding [1]. This paper proposes a micro fabrication process for polymer micro needles, using DLP based projection-based stereo lithography that is capable of fabricating micro-needles using biocompatible polymers. The fabrication in the experimental setup is performed with continuous movement of the platform in the vertical direction hence good surface quality is obtained. The influence of polymerization time, light intensity of DLP projector and chemical composition of the resins on the production speed and the geometrical accuracy of the micro needles have been studied. The length and the tip diameter of the micro needle are shown to be controlled through these factors. The length and tip diameter of the fabricated micro needles were observed using SEM and optical microscope and measured to be around 520 μm and 40 μm, respectively. The results indicate that polymer micro needles with appropriate geometry can be fabricated using this technique. © 2016 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license.Item Open Access Interlocking shish-kebab morphology in polybutene-1(John Wiley & Sons, Inc., 2002) Kalay, G.; Kalay, C. R.The aim of this research was to explore the effect of shear-controlled orientation injection molding (SCORIM) on polybutene-1 (PB-1). This article describes the methods and processing conditions used for injection molding and discusses the properties of the moldings. Both conventional and SCORIM have been used for the production of moldings. SCORIM is based on the application of specific macroscopic shears to a solidifying melt that facilitates enhanced molecular alignment. The effect of the process was investigated by performing mechanical tests, X-ray studies, differential scanning calorimetric studies, polarized light microscopy, and atomic force microscopy (AFM). Moldings exhibited an improved mechanical performance as compared with conventional moldings. Young's modulus was increased over twofold, and the impact energy was enhanced by 60%. The improvement in mechanical performance was combined with an increase in crystallinity and enhanced molecular orientation. The application of SCORIM also favored the formation of the stable Form I' in PB-1. The formation of interlocking shish-kebab morphology following the application of SCORIM was observed in the AFM studies. Relationships between the mechanical properties of PB-1 and the micromorphologies formed during processing are demonstrated.