Browsing by Subject "Force versus"
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Item Open Access A constrained, force-directed layout algorithm for biological pathways(Springer, Berlin, Heidelberg, 2004-09) Genç, Burkay; Doğrusöz, UğurWe present a new elegant algorithm for layout of biological signaling pathways. It uses a force-directed layout scheme, taking into account directional and regional constraints enforced by different molecular interaction types and subcellular locations in a cell. The algorithm has been successfully implemented as part of a pathway integration and analysis toolkit named PATIKA and results with respect to computational complexity and quality of the layout have been found satisfactory.