Browsing by Subject "Dementia"

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Open Access
Beckett'in ayak sesleri adlı tiyatro eserinde zihinde yankılanmalar
(Ürün Yayınları, 2016) Bayrakçeken-Akın, Aylin
Footfalls was written by Saınuel Beckett in 1975 and was first peıfoımed at the Royal Court Theah·e as part of the Samuel Beckett Festival on May 20, 1976. The play was directed by Beckett himself. There are two characters. These are May (M) and her mother Voice (V). However, the audience never sees V but hears her. The ınother is paralyzed and exists only through the care of May. May never leaves hoıne and constantly walks rhythmically on a hard wood floor. The two talk about daily routines, past memories and caring where the dialogues are fragınented, absurd and repetitive. The play consists of four parts and each paıi opens with bells chiming. As the stage darkens, May begins walking on a nine step sh·ip witb a width of one metre. In each part it gets darker and at the end the stage is in darlmess. May and her mother are not there anymore.
Open Access
Cognitive activity detection and tracing system
(KARE Publishing, Kare Yayıncılık, 2023-08-01) Yıldırım, Onur; Kandemir, Çağla; Kardaşlar, Emre; Sümer, Emre
Cognitive problems like Dementia and Alzheimer’s are usually challenging to diagnose but can be noticed by some signs of their symptoms. The most common symptoms are confusion, trouble finding the right word, memory loss, and difficulty concentrating. This study aims to design a cognitive activity detection and tracing system that contains games and analyzes users’ performances then displays detailed statistics to the users. The proposed Cognitive Activity Detection and Tracing System (CADTS) is software that contains different kinds of games from different categories inside its body that aims to measure cognitive activity by utilizing formulations in the context of the games and give feedback to users concerning the performance analyses done. The purpose of these analyses is to catch the signs of symptoms. An insight into a possible scoring system is provided, and as our results, several descriptive statistics are shared based on the tests conducted.
Open Access
Mammalian target of rapamycin (mTOR), aging, neuroscience, and their association with aging-related diseases
(Elsevier Inc., 2016) Celebi-Birand, Ergül Dilan; Karoğlu, Elif Tuğçe; Doldur-Ballı, Füsun; Adams, Michelle M.; Maiese, K.
Normal aging is accompanied by cognitive impairment with subtle cellular and molecular changes in the brain, whereas, pathological brain aging manifests as severe behavioral impairments with cellular pathology. Understanding the factors that contribute to both states is undoubtedly important for determining appropriate interventions that alter their progression. Mammalian target of rapamycin (mTOR) signaling has been implicated in affecting lifespan and age-related diseases such as cancer. The relationship of mTOR signaling with pathological brain aging has been more extensively studied, whereas the association with normal brain aging is not well understood. In this chapter we present information about normal and pathological brain aging, the relationship with mTOR signaling and use information from other age-related diseases to suggest that mTOR may have a role in promoting the cellular and molecular changes that underlie age-related cognitive changes. Future work should be directed towards understanding the precise role of mTOR signaling in brain aging. © 2016 Elsevier Inc. All rights reserved.