Browsing by Subject "Decision supports"

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Open Access
A comprehensive methodology for determining the most informative mammographic features
(2013) Wu, Y.; Alagoz O.; Ayvaci, M.U.S.; Munoz Del Rio, A.; Vanness, D.J.; Woods, R.; Burnside, E.S.
This study aims to determine the most informative mammographic features for breast cancer diagnosis using mutual information (MI) analysis. Our Health Insurance Portability and Accountability Act-approved database consists of 44,397 consecutive structured mammography reports for 20,375 patients collected from 2005 to 2008. The reports include demographic risk factors (age, family and personal history of breast cancer, and use of hormone therapy) and mammographic features from the Breast Imaging Reporting and Data System lexicon. We calculated MI using Shannon's entropy measure for each feature with respect to the outcome (benign/malignant using a cancer registry match as reference standard). In order to evaluate the validity of the MI rankings of features, we trained and tested naïve Bayes classifiers on the feature with tenfold cross-validation, and measured the predictive ability using area under the ROC curve (AUC). We used a bootstrapping approach to assess the distributional properties of our estimates, and the DeLong method to compare AUC. Based on MI, we found that mass margins and mass shape were the most informative features for breast cancer diagnosis. Calcification morphology, mass density, and calcification distribution provided predictive information for distinguishing benign and malignant breast findings. Breast composition, associated findings, and special cases provided little information in this task. We also found that the rankings of mammographic features with MI and AUC were generally consistent. MI analysis provides a framework to determine the value of different mammographic features in the pursuit of optimal (i.e., accurate and efficient) breast cancer diagnosis. © 2013 Society for Imaging Informatics in Medicine.
Open Access
Decision support for adopting SPLE with transit-PL
(ACM, 2013) Kalender, Mert Emin; Tüzün, E.; Tekinerdoğan, Bedir
It is generally acknowledged that the decision to adopt a software product line engineering (SPLE) approach needs to be performed carefully due to the di• erent risks involved in taking such an important decision. To mitigate the potential risks of the transition to SPLE, several studies have been proposed that include many di• erent rules for analyzing the feasibility of the SPLE adoption and the selection of transition process. However, it is not easy to apply these manually and likewise provide a proper decision with the corresponding justification. In this paper, we propose the tool Transit-PL, a web based decision support system for analyzing the feasibility of SPLE for an organization and selecting the appropriate transition strategy. Transit-PL provides a framework to build particular decision support system for selected strategies using di• erent types of questions and corresponding rules and set of answers. Copyright 2013 ACM.