Browsing by Author "Melik, Rohat"
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Item Open Access Metamaterial-based wireless RF-MEMS strain sensors(IEEE, 2010) Melik, Rohat; Ünal, Emre; Perkgoz, Nihan Kosku; Puttlitz, C.; Demir, Hilmi VolkanApproximately 10% of the fractures do not heal properly because of the inability to monitor fracture healing. Standard radiography is not capable of discriminating whether bone healing is occurring normally or aberrantly. We propose and develop an implantable wireless sensor that monitors strain on implanted hardware in real time telemetrically. This enables clinicians to monitor fracture healing. Here we present the development and demonstration of metamaterial-based radiofrequency (RF) micro-electro-mechanical system (MEMS) strain sensors for wireless strain sensing to monitor fracture healing. The operating frequency of these sensors shifts under mechanical loading; this shift is related to the surface strain of the implantable test material. In this work, we implemented metamaterials in two different architectures as bio-implantable wireless strain sensors for the first time. These custom-design metamaterials exhibit better performance as sensors than traditional RF structures (e.g., spiral coils) because of their unique structural properties (splits). They feature a low enough operating frequency to avoid the background absorption of soft tissue and yield higher Q-factors compared to the spiral structures (because their gaps have much higher electric field density). In our first metamaterial architecture of an 5x5 array, the wireless sensor shows high sensitivity (109kHz/kgf, 5.148kHz/microstrain) with low nonlinearity-error (<200microstrain). Using our second architecture, we then improved the structure of classical metamaterial and obtained nested metamaterials that incorporate multiple metamaterials in a compact nested structure and measured strain telemetrically at low operating frequencies. This novel nested metamaterial structure outperformed classical metamaterial structure as wireless strain sensors. By employing nested metamaterial architecture, the operating frequency is reduced from 529.8 MHz to 506.2 MHz while the sensitivity is increased from 0.72 kHz/kgf to 1.09 kHz/kgf. ©2010 IEEE.Item Open Access Novel wireless RF-bioMEMS implant sensors of metamaterials(2010) Melik, RohatToday approximately one out of ten patients with a major bone fracture does not heal properly because of the inability to monitor fracture healing. Standard radiography is not capable of discriminating whether bone healing is occurring normally or aberrantly. To solve this problem, we proposed and developed a new enabling technology of implantable wireless sensors that monitor mechanical strain on implanted hardware telemetrically in real time outside the body. This is intended to provide clinicians with a powerful capability to asses fracture healing following the surgical treatment. Here we present the proof-of-concept in vitro and ex vivo demonstrations of bio-compatible radio-frequency (RF) micro-electro-mechanical system (MEMS) strain sensors for wireless strain sensing to monitor healing process. The operating frequency of these sensors shifts under mechanical loading; this shift is related to the surface strain of the implantable test material. In this thesis, for the first time, we developed and demonstrated a new class of bio-implant metamaterial-based wireless strain sensors that make use of their unique structural advantages in sensing, opening up important directions for the applications of metamaterials. These custom-design metamaterials exhibit better performance in remote sensing than traditional RF structures (e.g., spiral coils). Despite their small size, these meta-sensors feature a low enough operating frequency to avoid otherwise strong background absorption of soft tissue and yet yield higher Q-factors (because of their splits with high electric field density) compared to the spiral structures. We also designed and fabricated flexible metamaterial sensors to exhibit a high level of linearity, which can also conveniently be used on non-flat surfaces. Innovating on the idea of integrating metamaterials, we proposed and implemented a novel architecture of ‘nested metamaterials’ that incorporate multiple split ring resonators integrated into a compact nested structure to measure strain telemetrically over a thick body of soft tissue. We experimentally verified that this nested metamaterial architecture outperforms classical metamaterial structures in telemetric strain sensing. As a scientific breakthrough, by employing our nested metamaterial design, we succeeded in reducing the electrical length of the sensor chip down to λo/400 and achieved telemetric operation across thick soft tissue with a tissue thickness up to 20 cm, while using only sub-cm implantable chip size (compatible with typical orthopaedic trauma implants and instruments). As a result, with nested metamaterials, we successfully demonstrated wireless strain sensing on sheep’s fractured metatarsal and femur using our sensors integrated on stainless steel fixation plates and on sheep’s spine using directly attached sensors in animal models. This depth of wireless sensing has proved to suffice for a vast portfolio of bone fracture (including spine) and trauma care applications in body, as also supported by ongoing in vivo experiments in live animal models in collaboration with biomechanical and medical doctors. Herein, for all generations of our RF-bioMEMS implant sensors, this dissertation presents a thorough documentation of the device conception, design, modeling, fabrication, device characterization, and system testing and analyses. This thesis work paves the way for “smart” orthopaedic trauma implants, and enables further possible innovations for future healthcare.