Feasibility of 3-dimensional sampling perfection with application optimized contrast sequence in the evaluation of patients with hydrocephalus

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buir.contributor.authorAlgın, Oktay
dc.citation.epage328en_US
dc.citation.issueNumber3en_US
dc.citation.spage321en_US
dc.citation.volumeNumber39en_US
dc.contributor.authorKartal, M. G.en_US
dc.contributor.authorOcakoglu, G.en_US
dc.contributor.authorAlgın, Oktayen_US
dc.date.accessioned2016-02-08T10:13:36Z
dc.date.available2016-02-08T10:13:36Z
dc.date.issued2015en_US
dc.departmentNational Magnetic Resonance Research Center (UMRAM)en_US
dc.departmentAysel Sabuncu Brain Research Center (BAM)en_US
dc.description.abstractPurpose This study aimed to investigate the effectiveness and additive value of T2W 3-dimensional sampling perfection with application optimized contrast (3D-SPACE) with variant flip-angle mode in imaging of all types of hydrocephalus. Our secondary objective was to assess the reliability of 3D-SPACE sequence and correspondence of the results with phase-contrast magnetic resonance imaging (PC-MRI)-based data. Materials and Methods Forty-one patients with hydrocephalus have undergone 3-T MRI. T2W 3D-SPACE sequence has been obtained in addition to routine hydrocephalus protocol. Cerebrospinal fluid circulation, presence/type/etiology of hydrocephalus, obstruction level scores, and diagnostic levels of confidence were evaluated separately by 2 radiologists. In the first session, routine sequences with PC-MRI were evaluated, and in another session, only 3D-SPACE and 3-dimensional magnetization prepared rapid acquisition gradient echo sequences were evaluated. Results obtained in these sessions were compared with each other and those obtained in consensus session. Results Agreement values were very good for both 3D-SPACE and PC-MRI sequences (P < 0.001 for all). Also, the correlation of more experienced reader's 3D-SPACE-based scores and consensus-based scores was perfect (κ = 1, P < 0.001).The mean value of PC-MRI-based confidence scores were lower than those obtained in 3D-SPACE and consensus sessions. Conclusions T2W 3D-SPACE sequence provides morphologic cerebrospinal fluid flow data. It is a noninvasive technique providing extensive multiplanar reformatted images with a lower specific absorption rate. These advantages over PC-MRI make 3D-SPACE sequence a promising tool in management of patients with hydrocephalus. © 2015 Wolters Kluwer Health, Inc.en_US
dc.identifier.doi10.1097/RCT.0000000000000206en_US
dc.identifier.issn0363-8715
dc.identifier.urihttp://hdl.handle.net/11693/23414
dc.language.isoEnglishen_US
dc.publisherLippincott Williams and Wilkinsen_US
dc.relation.isversionofhttps://doi.org/10.1097/RCT.0000000000000206en_US
dc.source.titleJournal of Computer Assisted Tomographyen_US
dc.subjectMRIen_US
dc.subject3D-SPACEen_US
dc.subjectVariable flip angleen_US
dc.subjectHydrocephalusen_US
dc.subjectPC cine MRen_US
dc.titleFeasibility of 3-dimensional sampling perfection with application optimized contrast sequence in the evaluation of patients with hydrocephalusen_US
dc.typeArticleen_US
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