Walking patterns in shopping malls : the case of Ankamall

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buir.advisorAkkaya, Engin U.
dc.contributor.authorPaykoç, Eda
dc.date.accessioned2016-01-08T18:19:12Z
dc.date.available2016-01-08T18:19:12Z
dc.date.issued2013
dc.departmentDepartment of Interior Architecture and Environmental Designen_US
dc.descriptionAnkara : The Department of Interior Architecture and Environmental Design, İhsan Doğramacı Bilkent University, 2013.en_US
dc.descriptionThesis (Master's) -- Bilkent University, 2013.en_US
dc.descriptionIncludes bibliographical references.en_US
dc.description.abstractSearch for new noninvasive methods for diseases has been significant question for years. Therapeutic properties of light are combined with proper chromophore in order to create fundamentals of photodynamic therapy which is a new treatment modality for cancer and other various non-oncological diseases. The method relies on the activation of photosensitizer by using light of certain wavelength and generation of cytotoxic singlet oxygen species in response. Reactive oxygen species kill the targeted tissue within smaller effective diameter through apoptosis/ necrosis mechanism. Through this method, new PDT agents can be proposed and their properties can be tuned by manipulation of other photophysical processes. In this thesis, synthesis, characterization novel water soluble, near IR absorbing Bodipy photosensitizer will be discussed. As opposed to other photosensitizers in literature, this photosensitizer is rationally designed to have singlet oxygen generation capability only in cancer tissue as a result of glutathione triggered activation.en_US
dc.description.degreeM.F.A.en_US
dc.description.statementofresponsibilityPaykoç, Edaen_US
dc.format.extentxi, 109 leaves, illustrationen_US
dc.identifier.urihttp://hdl.handle.net/11693/15482
dc.language.isoEnglishen_US
dc.publisherBilkent Universityen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBodipyen_US
dc.subjectphotodynamic therapyen_US
dc.subjectGlutathioneen_US
dc.subjectwater solubleen_US
dc.subject.lccNA6218 .P39 2013en_US
dc.subject.lcshShopping malls--Design and construction.en_US
dc.subject.lcshShopping malls--Turkey--Ankara--Case studies.en_US
dc.titleWalking patterns in shopping malls : the case of Ankamallen_US
dc.typeThesisen_US
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