• About
  • Policies
  • What is openaccess
  • Library
  • Contact
Advanced search
      View Item 
      •   BUIR Home
      • Scholarly Publications
      • Faculty of Business Administration
      • Department of Management
      • View Item
      •   BUIR Home
      • Scholarly Publications
      • Faculty of Business Administration
      • Department of Management
      • View Item
      JavaScript is disabled for your browser. Some features of this site may not work without it.

      Dynamic resource scheduling of biomanufacturing projects

      Thumbnail
      Embargo Lift Date: 2023-05-02
      View / Download
      935.6 Kb
      Author
      Limon, Yasemin
      Date
      2020-05-02
      Source Title
      Computers and Industrial Engineering
      Print ISSN
      0360-8352
      Publisher
      Elsevier
      Volume
      147
      Language
      English
      Type
      Article
      Item Usage Stats
      6
      views
      0
      downloads
      Abstract
      We consider the scheduling problem for biomanufacturing projects that involve multiple tasks and “no-wait” constraints between some of these tasks. The aim is to create schedules that ensure timely delivery of products while enabling schedule revisions to accommodate additional constraints realized during the execution of these projects. We formulate the problem as a mixed-integer linear programming model with the objective of minimizing total tardiness, and propose a dynamic scheduling approach that solves a series of modified mixed-integer linear programming models to revise and improve the schedule. We conduct numerical studies to investigate the performance of this approach and compare its performance to a traditional proactive scheduling approach. In collaboration with biomanufacturing companies, we create a scheduling tool and validate the approach with implementation in an industry setting.
      Keywords
      Dynamic scheduling
      Biomanufacturing
      Protein manufacturing
      No-wait
      Mixed-integer linear program
      Permalink
      http://hdl.handle.net/11693/75521
      Published Version (Please cite this version)
      https://doi.org/10.1016/j.cie.2020.106527
      Collections
      • Department of Management 567
      Show full item record

      Browse

      All of BUIRCommunities & CollectionsTitlesAuthorsAdvisorsBy Issue DateKeywordsTypeDepartmentsThis CollectionTitlesAuthorsAdvisorsBy Issue DateKeywordsTypeDepartments

      My Account

      Login

      Statistics

      View Usage StatisticsView Google Analytics Statistics

      Bilkent University

      If you have trouble accessing this page and need to request an alternate format, contact the site administrator. Phone: (312) 290 1771
      © Bilkent University - Library IT

      Contact Us | Send Feedback | Off-Campus Access | Admin | Privacy