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dc.contributor.advisorÇukur, Emine Ülkü Sarıtaş
dc.contributor.authorÇağıl, Ahmet Rahmetullah
dc.date.accessioned2021-01-15T07:10:07Z
dc.date.available2021-01-15T07:10:07Z
dc.date.copyright2020-12
dc.date.issued2020-12
dc.date.submitted2021-01-14
dc.identifier.urihttp://hdl.handle.net/11693/54890
dc.descriptionCataloged from PDF version of article.en_US
dc.descriptionThesis (Master's): Bilkent University, Department of Electrical and Electronics Engineering, İhsan Doğramacı Bilkent University, 2020.en_US
dc.descriptionIncludes bibliographical references (leaves 68-70).en_US
dc.description.abstractMagnetic Particle Imaging (MPI) is a relatively new biomedical imaging modality that can provide excellent sensitivity, contrast and resolution utilising superparamagnetic iron oxide nanoparticles. In MPI, spatial selectivity is achieved through selection fields created by either a permanent magnets or electromagnets. Selection fields generated by different arrangements of magnets result in different topologies of operation for MPI scanners. Among these scanner topologies, most prominent ones are Field Free Point (FFP) and Field Free Line (FFL) scanners, which differ in their advantages and disadvantages. Most importantly, FFL scanners provide improved sensitivity and rapid imaging, but offer only projection format images. FFP scanners offer 3D volumetric acquisition (and thus flexibility in acquiring an image from only a region or slice of interest), but can suffer from relatively lower sensitivity and longer scan times. In standard MPI scanners, as one topology has to be chosen when building a scanner, advantages of the other topology will be forgone. This thesis proposes a hybrid topology that functions as FFL by default, but can be swapped electronically into an FFP topology with the use of a saddle coil pair. This dual-topology scanner allows projection format images that can be used for rapid 2D projecton imaging or serve the purpose of a localizer, which can then be followed by 3D volumetric imaging of a region of interest. A preclinical hybrid scanner utilising the proposed topology is designed and constructed. Additionally, a novel double tuning mechanism that improves ease of tuning and allows for consistently achieving higher decoupling for gradiometer receive coils is introduced, built, and demonstrated.en_US
dc.description.statementofresponsibilityby Ahmet Rahmetullah Çağılen_US
dc.format.extentxv, 70 leaves : color charts ; 30 cm.en_US
dc.language.isoEnglishen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectMagnetic particle imagingen_US
dc.subjectDual-mode scanneren_US
dc.subjectField-free pointen_US
dc.subjectField-free lineen_US
dc.subjectGradiometer receive coilen_US
dc.titleA novel preclinical dual-topology magnetic particle imaging scanneren_US
dc.title.alternativeÖzgün bir çift topolojili klinik öncesi manyetik parçacık görüntüleme tarayıcısıen_US
dc.typeThesisen_US
dc.departmentDepartment of Electrical and Electronics Engineeringen_US
dc.publisherBilkent Universityen_US
dc.description.degreeM.S.en_US
dc.identifier.itemidB125493
dc.embargo.release2021-07-14


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