• About
  • Policies
  • What is openaccess
  • Library
  • Contact
Advanced search
      View Item 
      •   BUIR Home
      • Scholarly Publications
      • Aysel Sabuncu Brain Research Center (BAM)
      • View Item
      •   BUIR Home
      • Scholarly Publications
      • Aysel Sabuncu Brain Research Center (BAM)
      • View Item
      JavaScript is disabled for your browser. Some features of this site may not work without it.

      SNR dependence of optimal parameters for apparent diffusion coefficient measurements

      Thumbnail
      View / Download
      262.7 Kb
      Author
      Sarıtaş, Emine Ülkü
      Lee, J.
      Nishimura, D.
      Date
      2011
      Source Title
      IEEE Transactions on Medical Imaging
      Print ISSN
      0278-0062
      Publisher
      IEEE
      Volume
      30
      Issue
      2
      Pages
      424 - 437
      Language
      English
      Type
      Article
      Item Usage Stats
      75
      views
      40
      downloads
      Abstract
      Optimizing the diffusion-weighted imaging (DWI) parameters (i.e., the b -value and the number of image averages) to the tissue of interest is essential for producing high-quality apparent diffusion coefficient (ADC) maps. Previous investigation of this optimization was performed assuming Gaussian noise statistics for the ADC map, which is only valid for high signal-to-noise ratio (SNR) imaging. In this work, the true statistics of the noise in ADC maps are derived, followed by an optimization of the DWI parameters as a function of the imaging SNR. Specifically, it is demonstrated that the optimum b -value is a monotonically increasing function of the imaging SNR, which converges to the optimum b -value from previously proposed approaches for high-SNR cases, while exhibiting a significant deviation from this asymptote for low-SNR situations. Incorporating the effects of T 2 weighting further increases the SNR dependence of the optimal parameters. The proposed optimization scheme is particularly important for high-resolution DWI, which intrinsically suffers from low SNR and therefore cannot afford the use of the conventional high b -values. Comparison scans were performed for high-resolution DWI of the spinal cord, demonstrating the improvements in the resulting images and the ADC maps achieved by this method.
      Permalink
      http://hdl.handle.net/11693/53594
      Published Version (Please cite this version)
      https://doi.org/10.1109/TMI.2010.2084583
      Collections
      • Aysel Sabuncu Brain Research Center (BAM) 196
      Show full item record

      Browse

      All of BUIRCommunities & CollectionsTitlesAuthorsAdvisorsBy Issue DateKeywordsTypeDepartmentsThis CollectionTitlesAuthorsAdvisorsBy Issue DateKeywordsTypeDepartments

      My Account

      Login

      Statistics

      View Usage StatisticsView Google Analytics Statistics

      Bilkent University

      If you have trouble accessing this page and need to request an alternate format, contact the site administrator. Phone: (312) 290 1771
      Copyright © Bilkent University - Library IT

      Contact Us | Send Feedback | Off-Campus Access | Admin | Privacy