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      Tape'n roll inertial microfluidics

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      Embargo Lift Date: 2021-11-01
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      Author(s)
      Asghari, Mohammad
      Serhatlıoğlu, Murat
      Güler, M. T.
      Elbüken, Çağlar
      Date
      2019
      Source Title
      Sensors and Actuators A: Physical
      Print ISSN
      0924-4247
      Publisher
      Elsevier
      Volume
      299
      Pages
      111630-1 - 111630-9
      Language
      English
      Type
      Article
      Item Usage Stats
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      Abstract
      Particle focusing and separation in microfluidic devices are critical for biological and medical applications. Inertial microfluidics is used for high throughput bio-particle focusing and separation. Most of the inertial microfluidic systems use planar structures for squeezing the particles in streams. Particle manipulation in 3D structures is often overlooked due to the complexity of the fabrication. In this study, we introduce some novel microchannel designs for inertial microfluidics by using a simple fabrication method that allows construction of both 2D and 3D structures. First, inertial migration of particles in 2D layouts including straight, spiral, and square spiral channels is investigated. Afterward, by applying a “tape’n roll” method, helical and double oriented spiral channels are configured and unexplored inertial migration behaviours are observed. Thanks to the simplicity of the fabrication and the unique characteristics of the new designs, high performance microfluidic inertial migration results can be obtained without any need for complicated microfabrication steps. The design optimization cycle can also be shortened using a computational approach we introduce in this study.
      Keywords
      Particle focusing
      Inertial focusing
      3D microfluidics
      Flexible microfluidics
      Permalink
      http://hdl.handle.net/11693/53131
      Published Version (Please cite this version)
      https://doi.org/10.1016/j.sna.2019.111630
      Collections
      • Institute of Materials Science and Nanotechnology (UNAM) 2260
      • Nanotechnology Research Center (NANOTAM) 1179
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