A novel ODN delivery platform: CpG-ODN-loaded exosome nanovesicles
Abstract Book 2012, 10th CIMT Annual Meeting
Association for Cancer Immunotherapy
135 - 136
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Exosomes are naturally occurring, membranous nanovesicles of 40-100 nm in diameter. They arise from the endocytic cellular pathway through three stages: (i) formation of endocytic vesicles ii) multivesicular bodies (MVBs) formation in the cytosol and (iii) fusion of the MVBs with the plasma membrane to release their nanovesicular cargoes (1, 2).