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dc.contributor.authorKahraman, Tameren_US
dc.contributor.authorErkoçoğlu, M.en_US
dc.contributor.authorAzkur, D.en_US
dc.contributor.authorKocabaş, C. N.en_US
dc.contributor.authorGürsel, İhsanen_US
dc.coverage.spatialAntalya, Turkeyen_US
dc.descriptionConference Name: Molecular Immunology & Immunogenetics Congress, MIMIC 2012en_US
dc.descriptionDate of Conference: 27-29 April 2012en_US
dc.description.abstractMicroparticles (MPs) are nanovesicles secreted from wide variety of cells. They have role in cellular communications in addition to their physiological roles in several diseases. In this study, we investigated roles of MPs in allergic diseases. Method Peripheral blood from 43 asthma, 15 atopic dermatitis and 13 healthy subjects were collected. MPs were isolated via differential centrifugation and subjected to Annexin-V staining together with different cell specific surface markers (CD9, CD14, CD42a, CD69 and CD105) and analyzed by FACS. Internalization of MPs by PBMCs were assessed by SP-DiOC staining. Results FACS analysis demonstrated that number of MPs in ml plasma was 8,3 ± 1,5 x105, 3,2 ± 1,8 x105, 1,9 ± 0,8 x105, and 3,2 ± 2,2 x105 in healthy, atopic dermatitis, asthma controlled and asthma attack subjects, respectively.en_US
dc.source.titleMolecular Immunology & Immunogenetics Congress, MIMIC 2012en_US
dc.titleContribution of plasma microparticles to the clinical manifestation of allergic diseasesen_US
dc.typeConference Paperen_US
dc.departmentDepartment of Molecular Biology and Geneticsen_US
dc.publisherTurkish Society of Immunologyen_US

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