• About
  • Policies
  • What is openaccess
  • Library
  • Contact
Advanced search
      View Item 
      •   BUIR Home
      • Scholarly Publications
      • Institute of Materials Science and Nanotechnology (UNAM)
      • View Item
      •   BUIR Home
      • Scholarly Publications
      • Institute of Materials Science and Nanotechnology (UNAM)
      • View Item
      JavaScript is disabled for your browser. Some features of this site may not work without it.

      Nanomaterials for neural regeneration

      Thumbnail
      View / Download
      145.9 Kb
      Author
      Sever, Melike
      Mammadov, Büşra
      Geçer, Mevhibe
      Güler, Mustafa O.
      Tekinay, Ayşe B.
      Editor
      Güler, Mustafa O.
      Tekinay, Ayşe B.
      Date
      2016-03-11
      Publisher
      John Wiley & Sons
      Pages
      33 - 58
      Language
      English
      Type
      Book Chapter
      Item Usage Stats
      191
      views
      129
      downloads
      Book Title
      Therapeutic nanomaterials
      Abstract
      The central nervous system (CNS) consists of a dense network of cells leaving a smaller volume for the extracellular matrix (ECM) components (10‐20% for the brain unlike most other tissues (Cragg, 1979)). The reaction of the nervous tissue to any injury leading to scar tissue formation acts as a barrier for regeneration in the CNS, while it supports regeneration in the peripheral nervous system (PNS). By mimicking several unique characteristics of the natural environment of cells, synthetic materials for neural regeneration can be improved chemically and biologically. Especially bioactivation of materials can be achieved by addition of small chemical moieties to the scaffold particularly found in specific tissues or addition of biologically active molecules derived from natural ECM. The ECM‐derived short peptides are promising candidates to be presented as functional domains on the scaffold surface for use in neural regeneration.
      Keywords
      Biological functionalization
      Cellular behavior
      Central nervous system
      Chemical functionalization
      Electrical conductivity
      Extracellular matrix
      Nanomaterials
      Neural regeneration
      Peripheral nervous system
      Permalink
      http://hdl.handle.net/11693/50839
      Published Version (Please cite this version)
      https://doi.org/10.1002/9781118987483.ch3
      https://doi.org/10.1002/9781118987483
      Collections
      • Institute of Materials Science and Nanotechnology (UNAM) 1775
      • Nanotechnology Research Center (NANOTAM) 1006
      Show full item record

      Browse

      All of BUIRCommunities & CollectionsTitlesAuthorsAdvisorsBy Issue DateKeywordsTypeDepartmentsThis CollectionTitlesAuthorsAdvisorsBy Issue DateKeywordsTypeDepartments

      My Account

      Login

      Statistics

      View Usage StatisticsView Google Analytics Statistics

      Bilkent University

      If you have trouble accessing this page and need to request an alternate format, contact the site administrator. Phone: (312) 290 1771
      Copyright © Bilkent University - Library IT

      Contact Us | Send Feedback | Off-Campus Access | Admin | Privacy