The electromagnetic 2-D scattering from a single biological cell is analyzed by using Muller boundary integral equation (MBIE) method. The accuracy and smoothness of the solution are improved by applying Nystrom-type discretization. We present numerical results on a single biological cell during the different major phases of mitosis. The simulations show that the cell shape, as well as the cell orientation, have a large influence on the scattering properties of biological cell models.