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      Recent advances in bioactive 1D and 2D carbon nanomaterials for biomedical applications

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      Embargo Lift Date: 2019-10-01
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      Author
      Erol, Özlem
      Uyan, İdil
      Hatip, Meyem
      Yılmaz, Canelif
      Tekinay, Ayse B.
      Güler, Mustafa O.
      Date
      2018
      Source Title
      Nanomedicine: Nanotechnology, Biology, and Medicine
      Print ISSN
      1549-9634
      Publisher
      Elsevier
      Volume
      14
      Issue
      7
      Pages
      2433 - 2454
      Language
      English
      Type
      Review
      Item Usage Stats
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      Abstract
      One-dimensional (1D) carbon nanotubes (CNTs) and the two-dimensional (2D) graphene represent the most widely studied allotropes of carbon. Due to their unique structural, electrical, mechanical and optical properties, 1D and 2D carbon nanostructures are considered to be leading candidates for numerous applications in biomedical fields, including tissue engineering, drug delivery, bioimaging and biosensors. The biocompatibility and toxicity issues associated with these nanostructures have been a critical impediment for their use in biomedical applications. In this review, we present an overview of the various materials types, properties, functionalization strategies and characterization methods of 1D and 2D carbon nanomaterials and their derivatives in terms of their biomedical applications. In addition, we discuss various factors and mechanisms affecting their toxicity and biocompatibility.
      Keywords
      Biocompatibility
      Biomedical applications
      Carbon nanotube
      Graphene
      Graphene oxide
      Permalink
      http://hdl.handle.net/11693/49927
      Published Version (Please cite this version)
      https://doi.org/10.1016/j.nano.2017.03.021
      Collections
      • Aysel Sabuncu Brain Research Center (BAM) 207
      • Institute of Materials Science and Nanotechnology (UNAM) 1904
      • Nanotechnology Research Center (NANOTAM) 1055
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