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      • Department of Electrical and Electronics Engineering
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      Effects of duty cycle on magnetostimulation thresholds in MPI

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      Author
      Demirel, Omer Burak
      Sarıtaş, Emine Ülkü
      Date
      2017
      Source Title
      International Journal on Magnetic Particle Imaging
      Print ISSN
      2365-9033
      Publisher
      Infinite Science Publishing
      Volume
      3
      Issue
      1
      Pages
      1 - 7
      Language
      English
      Type
      Article
      Item Usage Stats
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      20
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      Abstract
      Magnetic Particle Imaging (MPI) relies on time-varying magnetic fields to generate an image of the spatial distribution of superparamagnetic iron oxide nanoparticles. However, these oscillating magnetic fields form electric field patterns within the body, which in turn can cause peripheral nerve stimulations (PNS), also known as magnetostimulation. To prevent potential safety hazards and to optimize the scanning parameters such as field-of-view (FOV) and scanning speed in MPI, the factors that affect drive field magnetostimulation limits need to be determined accurately. In this work, we investigate the effects of the duty cycle on magnetostimulation thresholds in MPI. We performed human subject experiments by using a highly homogenous solenoidal coil on the upper arm of six subjects. Six different duty cycles ranging between 5 % and 100 % were applied at 25 kHz. Accordingly, magnetostimulation limits first decrease and then increase with increasing duty cycle, reaching a maximum at 100 % duty cycle. Since high duty cycles would be the preferred operating mode for rapid imaging with MPI, these results have promising implications for future human-sized MPI systems.
      Keywords
      Magnetostimulation threshold
      Peripheral nerve stimulation
      Duty cycle
      Magnetic particle imaging
      Permalink
      http://hdl.handle.net/11693/49285
      Published Version (Please cite this version)
      https://doi.org/10.18416/ijmpi.2017.1703010
      Collections
      • Aysel Sabuncu Brain Research Center (BAM) 183
      • Department of Electrical and Electronics Engineering 3524
      • National Magnetic Resonance Research Center (UMRAM) 175
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