Effects of duty cycle on magnetostimulation thresholds in MPI
Author
Demirel, Omer Burak
Sarıtaş, Emine Ülkü
Date
2017Source Title
International Journal on Magnetic Particle Imaging
Print ISSN
2365-9033
Publisher
Infinite Science Publishing
Volume
3
Issue
1
Pages
1 - 7
Language
English
Type
ArticleItem Usage Stats
73
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Abstract
Magnetic Particle Imaging (MPI) relies on time-varying magnetic fields to generate an image of the spatial distribution of superparamagnetic iron oxide nanoparticles. However, these oscillating magnetic fields form electric field
patterns within the body, which in turn can cause peripheral nerve stimulations (PNS), also known as magnetostimulation. To prevent potential safety hazards and to optimize the scanning parameters such as field-of-view (FOV)
and scanning speed in MPI, the factors that affect drive field magnetostimulation limits need to be determined
accurately. In this work, we investigate the effects of the duty cycle on magnetostimulation thresholds in MPI. We
performed human subject experiments by using a highly homogenous solenoidal coil on the upper arm of six
subjects. Six different duty cycles ranging between 5 % and 100 % were applied at 25 kHz. Accordingly, magnetostimulation limits first decrease and then increase with increasing duty cycle, reaching a maximum at 100 % duty
cycle. Since high duty cycles would be the preferred operating mode for rapid imaging with MPI, these results have
promising implications for future human-sized MPI systems.
Keywords
Magnetostimulation thresholdPeripheral nerve stimulation
Duty cycle
Magnetic particle imaging