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dc.contributor.authorDemir, Emeken_US
dc.contributor.authorCary, M. P.en_US
dc.contributor.authorPaley, S.en_US
dc.contributor.authorFukuda, K.en_US
dc.contributor.authorLemer, C.en_US
dc.contributor.authorVastrik, I.en_US
dc.contributor.authorWu, G.en_US
dc.contributor.authorD'Eustachio, P.en_US
dc.contributor.authorSchaefer, C.en_US
dc.contributor.authorLuciano, J.en_US
dc.contributor.authorSchacherer, F.en_US
dc.contributor.authorMartinez-Flores, I.en_US
dc.contributor.authorHu, Z.en_US
dc.contributor.authorJimenez-Jacinto, V.en_US
dc.contributor.authorJoshi-Tope, G.en_US
dc.contributor.authorKandasamy, K.en_US
dc.contributor.authorLopez-Fuentes, A. C.en_US
dc.contributor.authorMi, H.en_US
dc.contributor.authorPichler, E.en_US
dc.contributor.authorRodchenkov, I.en_US
dc.contributor.authorSplendiani, A.en_US
dc.contributor.authorTkachev, S.en_US
dc.contributor.authorZucker, J.en_US
dc.contributor.authorGopinath, G.en_US
dc.contributor.authorRajasimha, H.en_US
dc.contributor.authorRamakrishnan, R.en_US
dc.contributor.authorShah, I.en_US
dc.contributor.authorSyed, M.en_US
dc.contributor.authorAnwar, N.en_US
dc.contributor.authorBabur, Özgünen_US
dc.contributor.authorBlinov, M.en_US
dc.contributor.authorBrauner, E.en_US
dc.contributor.authorCorwin, D.en_US
dc.contributor.authorDonaldson, S.en_US
dc.contributor.authorGibbons, F.en_US
dc.contributor.authorGoldberg, R.en_US
dc.contributor.authorHornbeck, P.en_US
dc.contributor.authorLuna, A.en_US
dc.contributor.authorMurray-Rust, P.en_US
dc.contributor.authorNeumann, E.en_US
dc.contributor.authorReubenacker, O.en_US
dc.contributor.authorSamwald, M.en_US
dc.contributor.authorIersel, Martijn vanen_US
dc.contributor.authorWimalaratne, S.en_US
dc.contributor.authorAllen, K.en_US
dc.contributor.authorBraun, B.en_US
dc.contributor.authorWhirl-Carrillo, M.en_US
dc.contributor.authorCheung, Kei-Hoien_US
dc.contributor.authorDahlquist, K.en_US
dc.contributor.authorFinney, A.en_US
dc.contributor.authorGillespie, M.en_US
dc.contributor.authorGlass, E.en_US
dc.contributor.authorGong, L.en_US
dc.contributor.authorHaw, R.en_US
dc.contributor.authorHonig, M.en_US
dc.contributor.authorHubaut, O.en_US
dc.contributor.authorKane, D.en_US
dc.contributor.authorKrupa, S.en_US
dc.contributor.authorKutmon, M.en_US
dc.contributor.authorLeonard, J.en_US
dc.contributor.authorMarks, D.en_US
dc.contributor.authorMerberg, D.en_US
dc.contributor.authorPetri, V.en_US
dc.contributor.authorPico, A.en_US
dc.contributor.authorRavenscroft, D.en_US
dc.contributor.authorRen, L.en_US
dc.contributor.authorShah, N.en_US
dc.contributor.authorSunshine, M.en_US
dc.contributor.authorTang R.en_US
dc.contributor.authorWhaley, R.en_US
dc.contributor.authorLetovksy, S.en_US
dc.contributor.authorBuetow, K. H.en_US
dc.contributor.authorRzhetsky, A.en_US
dc.contributor.authorSchachter, V.en_US
dc.contributor.authorSobral, B. S.en_US
dc.contributor.authorDoğrusöz, Uğuren_US
dc.contributor.authorMcWeeney, S.en_US
dc.contributor.authorAladjem, M.en_US
dc.contributor.authorBirney, E.en_US
dc.contributor.authorCollado-Vides, J.en_US
dc.contributor.authorGoto, S.en_US
dc.contributor.authorHucka, M.en_US
dc.contributor.authorNovère, Nicolas Leen_US
dc.contributor.authorMaltsev, N.en_US
dc.contributor.authorPandey, A.en_US
dc.contributor.authorThomas, P.en_US
dc.contributor.authorWingender, E.en_US
dc.contributor.authorKarp, P. D.en_US
dc.contributor.authorSander, C.en_US
dc.contributor.authorBader, G. D.en_US
dc.date.accessioned2018-04-12T13:49:34Z
dc.date.available2018-04-12T13:49:34Z
dc.date.issued2010-09en_US
dc.identifier.issn1087-0156
dc.identifier.urihttp://hdl.handle.net/11693/38163
dc.description.abstractBiological Pathway Exchange (BioPAX) is a standard language to represent biological pathways at the molecular and cellular level and to facilitate the exchange of pathway data. The rapid growth of the volume of pathway data has spurred the development of databases and computational tools to aid interpretation; however, use of these data is hampered by the current fragmentation of pathway information across many databases with incompatible formats. BioPAX, which was created through a community process, solves this problem by making pathway data substantially easier to collect, index, interpret and share. BioPAX can represent metabolic and signaling pathways, molecular and genetic interactions and gene regulation networks. Using BioPAX, millions of interactions, organized into thousands of pathways, from many organisms are available from a growing number of databases. This large amount of pathway data in a computable form will support visualization, analysis and biological discovery. © 2010 Nature America, Inc. All rights reserved.en_US
dc.language.isoEnglishen_US
dc.source.titleNature Biotechnologyen_US
dc.relation.isversionofhttp://dx.doi.org/10.1038/nbt.1666en_US
dc.subjectBiological discoveriesen_US
dc.subjectBiological pathwaysen_US
dc.subjectCellular levelsen_US
dc.subjectCommunity standardsen_US
dc.subjectComputational toolsen_US
dc.subjectData sharingen_US
dc.subjectGene regulation networken_US
dc.subjectGenetic interactionen_US
dc.subjectRapid growthen_US
dc.subjectSignaling pathwaysen_US
dc.subjectDatabase systemsen_US
dc.subjectVisualizationen_US
dc.subjectData visualizationen_US
dc.subjectMessenger RNAen_US
dc.subjectProtein kinase Ben_US
dc.subjectBiological pathway exchangeen_US
dc.subjectCopy number variationen_US
dc.subjectDatabaseen_US
dc.subjectEnzyme substrateen_US
dc.subjectFragmentation reactionen_US
dc.subjectMetabolismen_US
dc.subjectMolecular biologyen_US
dc.subjectMolecular dynamicsen_US
dc.subjectMolecular evolutionen_US
dc.subjectMolecular interactionen_US
dc.subjectPriority journalen_US
dc.subjectPromoter regionen_US
dc.subjectProtein DNA interactionen_US
dc.subjectProtein expressionen_US
dc.subjectProtein modificationen_US
dc.subjectProtein protein interactionen_US
dc.subjectProtein structureen_US
dc.subjectReviewen_US
dc.subjectSemanticsen_US
dc.subjectSingle nucleotide polymorphismen_US
dc.subjectStructure analysisen_US
dc.subjectComputational biologyen_US
dc.subjectDatabases as topicen_US
dc.subjectInformation disseminationen_US
dc.subjectMetabolic networks and pathwaysen_US
dc.subjectProgramming languagesen_US
dc.subjectSignal transductionen_US
dc.subjectSoftwareen_US
dc.titleThe BioPAX community standard for pathway data sharingen_US
dc.typeArticleen_US
dc.departmentDepartment of Computer Engineeringen_US
dc.departmentBilkent Center for Bioinformatics (BCBI)
dc.citation.spage935en_US
dc.citation.epage942en_US
dc.citation.volumeNumber28en_US
dc.citation.issueNumber9en_US
dc.identifier.doi10.1038/nbt.1666en_US
dc.publisherNature Publishing Groupen_US
dc.contributor.bilkentauthorDemir, Emek
dc.contributor.bilkentauthorBabur, Özgün
dc.contributor.bilkentauthorDoğrusöz, Uğur


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