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dc.contributor.authorToulopoulou, T.en_US
dc.contributor.authorPicchioni, M.en_US
dc.contributor.authorMortensen, P. B.en_US
dc.contributor.authorPetersen, L.en_US
dc.date.accessioned2018-04-12T11:04:12Z
dc.date.available2018-04-12T11:04:12Z
dc.date.issued2017en_US
dc.identifier.issn0586-7614
dc.identifier.urihttp://hdl.handle.net/11693/37150en_US
dc.description.abstractExposure to an urban environment during early life and low IQ are 2 well-established risk factors for schizophrenia. It is not known, however, how these factors might relate to one another. Data were pooled from the North Jutland regional draft board IQ assessments and the Danish Conscription Registry for men born between 1955 and 1993. Excluding those who were followed up for less than 1 year after the assessment yielded a final cohort of 153 170 men of whom 578 later developed a schizophrenia spectrum disorder. We found significant effects of having an urban birth, and also experiencing an increase in urbanicity before the age of 10 years, on adult schizophrenia risk. The effect of urban birth was independent of IQ. However, there was a significant interaction between childhood changes in urbanization in the first 10 years and IQ level on the future adult schizophrenia risk. In short, those subjects who moved to more or less urban areas before their 10th birthday lost the protective effect of IQ. When thinking about adult schizophrenia risk, the critical time window of childhood sensitivity to changes in urbanization seems to be linked to IQ. Given the prediction that by 2050, over 80% of the developed world's population will live in an urban environment, this represents a major future public health issue.en_US
dc.source.titleSchizophrenia Bulletinen_US
dc.relation.isversionofhttp://dx.doi.org/10.1093/schbul/sbw147en_US
dc.subjectFuture schizophrenia risken_US
dc.subjectIQen_US
dc.subjectPopulation studyen_US
dc.subjectUrban birthen_US
dc.subjectUrbanicity changes in childhooden_US
dc.titleIQ, the urban environment, and their impact on future schizophrenia risk in menen_US
dc.typeArticleen_US
dc.departmentDepartment of Psychologyen_US
dc.citation.spage1056en_US
dc.citation.epage1063en_US
dc.citation.volumeNumber43en_US
dc.citation.issueNumber5en_US
dc.identifier.doi10.1093/schbul/sbw147en_US
dc.publisherOxford University Pressen_US
dc.identifier.eissn1745-1701


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