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dc.contributor.authorBanerjee, S.en_US
dc.contributor.authorNishimura, D. G.en_US
dc.contributor.authorShankaranarayanan, A.en_US
dc.contributor.authorSaritas, E. U.en_US
dc.date.accessioned2018-04-12T10:58:21Z
dc.date.available2018-04-12T10:58:21Z
dc.date.issued2016en_US
dc.identifier.issn0740-3194
dc.identifier.urihttp://hdl.handle.net/11693/36955
dc.description.abstractPurpose: Reduced field-of-view (rFOV) diffusion-weighted imaging (DWI) using 2D echo-planar radiofrequency (2DRF) excitation has been widely and successfully applied in clinical settings. The purpose of this work is to further improve its clinical utility by overcoming slice coverage limitations without any scan time penalty while providing robust fat suppression. Theory and Methods: During multislice imaging with 2DRF pulses, periodic sidelobes in the slice direction cause partial saturation, limiting the slice coverage. In this work, a tilting of the excitation plane is proposed to push the sidelobes out of the imaging section while preserving robust fat suppression. The 2DRF pulse is designed using Shinnar-Le Roux algorithm on a rotated excitation k-space. The performance of the method is validated via simulations, phantom experiments, and high in-plane resolution in vivo DWI of the spinal cord. Results: Results show that rFOV DWI using the tilted 2DRF pulse provides increased signal-to-noise ratio, extended coverage, and robust fat suppression, without any scan time penalty. Conclusion: Using a tilted 2DRF excitation, a high-resolution rFOV DWI method with robust fat suppression and unrestricted slice coverage is presented. This method will be beneficial in clinical applications needing large slice coverage, for example, axial imaging of the spine, prostate, or breast. Magn Reson Med 76:1668–1676, 2016. © 2016 International Society for Magnetic Resonance in Medicine. © 2016 International Society for Magnetic Resonance in Medicineen_US
dc.language.isoEnglishen_US
dc.source.titleMagnetic resonance in medicineen_US
dc.relation.isversionofhttp://dx.doi.org/10.1002/mrm.26405en_US
dc.subject2D RF pulseen_US
dc.subjectfat suppressionen_US
dc.subjectmultislice imagingen_US
dc.subject2D echo planar radiofrequency excitationen_US
dc.subjectalgorithmen_US
dc.subjectbreasten_US
dc.subjectfeasibility studyen_US
dc.subjecthumanen_US
dc.subjecthuman experimenten_US
dc.subjectimage analysisen_US
dc.subjectimage qualityen_US
dc.subjectimaging and displayen_US
dc.subjectimaging phantomen_US
dc.subjectin vivo studyen_US
dc.subjectnuclear magnetic resonance scanneren_US
dc.subjectprostateen_US
dc.subjectradiofrequencyen_US
dc.subjectradiological parametersen_US
dc.subjectreduced field of viewen_US
dc.subjectrobust fat suppressionen_US
dc.subjectsidelobeen_US
dc.subjectsignal noise ratioen_US
dc.subjectsimulationen_US
dc.subjectslice coverageen_US
dc.subjectspinal corden_US
dc.subjectanatomy and histologyen_US
dc.subjectcomputer assisted diagnosisen_US
dc.subjectdevicesen_US
dc.subjectdiffusion weighted imagingen_US
dc.subjectevaluation studyen_US
dc.subjectimage subtractionen_US
dc.subjectproceduresen_US
dc.subjectreproducibilityen_US
dc.subjectAdipose Tissueen_US
dc.subjectAlgorithmsen_US
dc.subjectDiffusion Magnetic Resonance Imagingen_US
dc.subjectHumansen_US
dc.subjectImage Enhancementen_US
dc.subjectImage Interpretation, Computer-Assisteden_US
dc.subjectPhantoms, Imagingen_US
dc.subjectReproducibility of Resultsen_US
dc.subjectSensitivity and Specificityen_US
dc.subjectSignal Processing, Computer-Assisteden_US
dc.subjectSubtraction Techniqueen_US
dc.titleReduced field-of-view DWI with robust fat suppression and unrestricted slice coverage using tilted 2D RF excitationen_US
dc.typeArticleen_US
dc.departmentDepartment of Electrical and Electronics Engineeringen_US
dc.departmentUMRAM – National Magnetic Resonance Research Center
dc.citation.spage1668en_US
dc.citation.epage1676en_US
dc.citation.volumeNumber76en_US
dc.citation.issueNumber6en_US
dc.identifier.doi10.1002/mrm.26405en_US
dc.publisherJohn Wiley and Sons Inc.en_US


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