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dc.contributor.authorBuyukdagli S.en_US
dc.contributor.authorAla-Nissila T.en_US
dc.date.accessioned2018-04-12T10:47:24Z
dc.date.available2018-04-12T10:47:24Z
dc.date.issued2016en_US
dc.identifier.issn0021-9606
dc.identifier.urihttp://hdl.handle.net/11693/36658
dc.description.abstractWe probe the electrostatic cost associated with the approach phase of DNA translocation events. Within an analytical theory at the Debye-Hückel level, we calculate the electrostatic energy of a rigid DNA molecule interacting with a dielectric membrane. For carbon or silicon based low permittivity neutral membranes, the DNA molecule experiences a repulsive energy barrier between 10 kBT and 100 kBT. In the case of engineered membranes with high dielectric permittivities, the membrane surface attracts the DNA with an energy of the same magnitude. Both the repulsive and attractive interactions result from image-charge effects and their magnitude survive even for the thinnest graphene-based membranes of size d ≈ 6 Å. For weakly charged membranes, the electrostatic energy is always attractive at large separation distances but switches to repulsive close to the membrane surface. We also characterise the polymer length dependence of the interaction energy. For specific values of the membrane charge density, low permittivity membranes repel short polymers but attract long polymers. Our results can be used to control the strong electrostatic energy of DNA-membrane interactions prior to translocation events by chemical engineering of the relevant system parameters.en_US
dc.language.isoEnglishen_US
dc.source.titleThe Journal of Chemical Physicsen_US
dc.relation.isversionofhttp://dx.doi.org/10.1063/1.4942177en_US
dc.subjectCarbonen_US
dc.subjectDNAen_US
dc.subjectElectrostaticsen_US
dc.subjectEnergy barriersen_US
dc.subjectGrapheneen_US
dc.subjectMoleculesen_US
dc.subjectPermittivityen_US
dc.subjectPolymersen_US
dc.subjectAnalytical theoryen_US
dc.subjectAttractive interactionsen_US
dc.subjectDielectric membranesen_US
dc.subjectDNA translocation eventsen_US
dc.subjectElectrostatic energiesen_US
dc.subjectImage-charge effectsen_US
dc.subjectInteraction energiesen_US
dc.subjectSeparation distancesen_US
dc.subjectMembranesen_US
dc.subjectDNAen_US
dc.subjectGraphiteen_US
dc.subjectPolymeren_US
dc.subjectChemistryen_US
dc.subjectStatic electricityen_US
dc.subjectDNAen_US
dc.subjectGraphiteen_US
dc.subjectPolymersen_US
dc.subjectStatic Electricityen_US
dc.titleElectrostatic energy barriers from dielectric membranes upon approach of translocating DNA moleculesen_US
dc.typeArticleen_US
dc.departmentDepartment of Physics
dc.citation.spage084902-1en_US
dc.citation.epage084902-11en_US
dc.citation.volumeNumber144en_US
dc.citation.issueNumber8en_US
dc.identifier.doi10.1063/1.4942177en_US
dc.publisherA I P Publishing LLCen_US
dc.identifier.eissn1089-7690


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