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dc.contributor.authorDemir, B.en_US
dc.contributor.authorKahyaoglu, I.en_US
dc.contributor.authorGuvenir, A.en_US
dc.contributor.authorYerebasmaz, N.en_US
dc.contributor.authorAltinbas, S.en_US
dc.contributor.authorDilbaz, B.en_US
dc.contributor.authorDilbaz, S.en_US
dc.contributor.authorMollamahmutoglu, L.en_US
dc.date.accessioned2018-04-12T10:45:14Z
dc.date.available2018-04-12T10:45:14Z
dc.date.issued2016en_US
dc.identifier.issn0951-3590
dc.identifier.urihttp://hdl.handle.net/11693/36587
dc.description.abstractObjective: The aim of the presented study is to investigate the impact of progesterone change in the late follicular phase on the pregnancy rates of both agonist and antagonist protocols in normoresponders.Study design: A total of 201 normoresponder patients, who underwent embryo transfer were consecutively selected. 118 patients were stimulated using a long luteal GnRH agonist protocol and 83 using a flexible antagonist protocol. The level of change in late follicular phase progesterone was calculated according to the progesterone levels on the hCG day and pre-hCG day (1 or 2 days prior to hCG day) measurement.Results: Clinical pregnancy rates were comparable between long luteal and antagonist group (35.6 and 41%, respectively). The incidence of progesterone elevation on the hCG day was 11% in long luteal and 18% in antagonist group (p = 0.16). In pregnant cycles, p levels both on the hCG day and pre-hCG day measurement were significantly higher in antagonist than agonist cycles (p = 0.029, p = 0.038, respectively). The change of p level was statistically significant in non-pregnant cycles both for the agonist (-0.17 ± 0.07; 95% CI: -0.29 to -0.37) and antagonist groups (-0.18 ± 0.07; 95%CI: -0.31 to -0.04).Conclusions: Late follicular phase progesterone levels were stable during the cycles of pregnant patients irrespective of the protocols and were shown to be higher in pregnant patients in antagonist cycles when compared to agonist cycles.en_US
dc.language.isoEnglishen_US
dc.source.titleGynecological Endocrinologyen_US
dc.relation.isversionofhttp://dx.doi.org/10.3109/09513590.2015.1121226en_US
dc.subjectGnRH antagonisten_US
dc.subjectIn-vitro fertilizationen_US
dc.subjectIntracytoplasmic sperm injectionen_US
dc.subjectProgesteroneen_US
dc.subjectChorionic gonadotropinen_US
dc.subjectEstradiolen_US
dc.subjectFollitropinen_US
dc.subjectGonadorelin agonisten_US
dc.subjectLuteinizing hormoneen_US
dc.subjectProgesteroneen_US
dc.subjectCetrorelixen_US
dc.subjectFollitropinen_US
dc.subjectGanirelixen_US
dc.subjectGonadorelinen_US
dc.subjectHormone antagonisten_US
dc.subjectLeuprorelinen_US
dc.subjectLuteinizing hormoneen_US
dc.subjectProgesteroneen_US
dc.subjectAdulten_US
dc.subjectControlled studyen_US
dc.subjectEmbryo transferen_US
dc.subjectFemaleen_US
dc.subjectFertilization in vitroen_US
dc.subjectFollicular phaseen_US
dc.subjectHumanen_US
dc.subjectIncidenceen_US
dc.subjectIntracytoplasmic sperm injectionen_US
dc.subjectLuteal phaseen_US
dc.subjectMajor clinical studyen_US
dc.subjectPregnancy rateen_US
dc.subjectPriority journalen_US
dc.subjectProgesterone blood levelen_US
dc.subjectAnalogs and derivativesen_US
dc.subjectAntagonists and inhibitorsen_US
dc.subjectBlooden_US
dc.subjectCase control studyen_US
dc.subjectFollicular phaseen_US
dc.subjectOvulation inductionen_US
dc.subjectPregnancyen_US
dc.subjectProceduresen_US
dc.subjectCase-control studiesen_US
dc.subjectEmbryo transferen_US
dc.subjectFemaleen_US
dc.subjectFollicle stimulating hormoneen_US
dc.subjectFollicular phaseen_US
dc.subjectGonadotropin-releasing hormoneen_US
dc.subjectHormone antagonistsen_US
dc.subjectHumansen_US
dc.subjectLeuprolideen_US
dc.subjectLuteinizing Hormoneen_US
dc.subjectOvulation Inductionen_US
dc.subjectPregnancyen_US
dc.subjectPregnancy Rateen_US
dc.subjectProgesteroneen_US
dc.subjectSperm Injectionsen_US
dc.subjectIntracytoplasmicen_US
dc.titleProgesterone change in the late follicular phase affects pregnancy rates both agonist and antagonist protocols in normoresponders: a case-controlled study in ICSI cyclesen_US
dc.typeArticleen_US
dc.departmentDepartment of Computer Engineering
dc.citation.spage361en_US
dc.citation.epage365en_US
dc.citation.volumeNumber32en_US
dc.citation.issueNumber5en_US
dc.identifier.doi10.3109/09513590.2015.1121226en_US
dc.publisherTaylor & Francisen_US
dc.identifier.eissn1473-0766


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