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dc.contributor.advisorÇukur, Emine Ülkü Sarıtaş
dc.contributor.authorMuslu, Yavuz
dc.date.accessioned2018-01-25T13:46:34Z
dc.date.available2018-01-25T13:46:34Z
dc.date.copyright2018-01
dc.date.issued2018-01
dc.date.submitted2018-01-25
dc.identifier.urihttp://hdl.handle.net/11693/35749
dc.descriptionCataloged from PDF version of article.en_US
dc.descriptionThesis (M.S.): Bilkent University, Department of Electrical and Electronics Engineering, İhsan Doğramacı Bilkent University, 2018.en_US
dc.descriptionIncludes bibliographical references (leaves 45-51).en_US
dc.description.abstractMagnetic Particle Imaging (MPI) is a novel biomedical imaging modality that shows great potential in terms of sensitivity, resolution, and contrast. Since its first introduction in 2005, several applications of MPI have already been demonstrated such as angiography, stem cell tracking, and cancer imaging. Recently, multi-color MPI techniques have been proposed to increase the functionality of MPI, where different nanoparticles are distinguished according to the differences in their responses to oscillating magnetic fields. These methods can also be extended to probe environmental factors such as viscosity and temperature, provided that the responses of different nanoparticles or nanoparticles in different environments are pre-calibrated. This thesis proposes a new multi-color MPI technique that does not require a calibration phase. This new technique directly estimates the relaxation time constants of nanoparticles to distinguish nanoparticle types and environmental factors from the MPI signal, and generates a multi-color relaxation map. The validity of the proposed technique is confirmed through an extensive experimental work with an in-house Magnetic Particle Spectrometer (MPS) at 10.8 kHz and an in-house MPI scanner at 9.7 kHz drive field frequencies, successfully distinguishing different nanoparticle types. The proposed calibration-free multi-color MPI technique is a promising method for future functional imaging applications of MPI.en_US
dc.description.statementofresponsibilityby Yavuz Muslu.en_US
dc.format.extentxviii, 61 leaves : charts (some color) ; 30 cmen_US
dc.language.isoEnglishen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectMagnetic Particle Imagingen_US
dc.subjectMulti-Color MPIen_US
dc.subjectMagnetic Nanoparticle Relaxationen_US
dc.subjectDirect Estimationen_US
dc.subjectMirror Symmteryen_US
dc.titleRelaxation mapping in magnetic particle imagingen_US
dc.title.alternativeManyetik parçacık görüntülemede relaksasyon haritalamaen_US
dc.typeThesisen_US
dc.departmentDepartment of Electrical and Electronics Engineeringen_US
dc.publisherBilkent Universityen_US
dc.description.degreeM.S.en_US
dc.identifier.itemidB157530
dc.embargo.release2019-01-12


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