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dc.contributor.advisorTuncel, Dönüş
dc.contributor.authorKöken, Emre
dc.date.accessioned2016-08-29T11:44:18Z
dc.date.available2016-08-29T11:44:18Z
dc.date.copyright2016-08
dc.date.issued2016-08
dc.date.submitted2016-08-10
dc.identifier.urihttp://hdl.handle.net/11693/32182
dc.descriptionCataloged from PDF version of article.en_US
dc.descriptionThesis (M.S.): Bilkent University, Department of Materials Science and Nanotechnology, İhsan Doğramacı Bilkent University, 2016.en_US
dc.descriptionIncludes bibliographical references (leaves 73-83).en_US
dc.description.abstractThis project firstly aims to develop water dispersible conjugated nanoparticles by reprecipitation method for FRET based white light emission. Preliminary NPs study with only OFT Pgy and only OFVBt N3 were done in order to determine size and distribution of NPs. Overlapping optical properties of donor (OFT Pgy) and acceptor (OFVBt N3) give possibility to FRET applications. By click reaction in water, terminal sites of oligomers are connected and white emission is sealed by keeping D-A pair close. FRET based white light is widely used in optoelectronic applications such as OLEDs or more specifically WOLEDs. Since the white light covers all visible spectrum, different color emissions are obtainable depending on excitation wavelength. Various biosensor and bioimaging applications are also possible with white light emitting NPs, since they are readily and stably dispersed in water. In second part of the project, OFVBt N3 oligomer is cross-linked with di-sulfide containing crosslinker via copper catalyzed click reaction. NPs were synthesized in THF to obtain high click efficiency and redispersed in water, since the biological applications are targeted. OFVBt N3 oligomer is advantageous for bioimaging with its red emission close to IR region, since lower frequency emission overcomes the background auto-fluorescence and penetrates deeper in the body. Di-sulfide crosslinker, in addition to connecting the oligomer molecules and stabilizing NPs, provides possibility of drug delivery application. Since GSH (glutathione) or Trx (thioredoxin) like thiol bearing bio-molecules subsist in higher concentrations in tumorous tissues, di-sulfide bond can be cleaved, releasing the loaded drug from NPs. Thus, crosslinked OFVBt N3 NPs is a theranostic agent with an advantageous emission color for bio-imaging and a cleavable di-sulfide bond for drug delivery & controlled release. In last part of the study, white light emitting bi-oligomer nanoparticles were designed and obtained by using OFB Pgy and Porph N3. A quality white emission requires to cover all visible spectrum and overlapping optical properties of OFB Pgy (D) and Porph N3 (A) is used to white light emission by FRET. The purpose of clicking the oligomer pair is to stabilize the FRET efficiency. Moreover, using THF as the solvent is not only facilitated a better click chemistry, but also provided ease of applicability for solid state white light applications. Since THF evaporates easily, white light emitting NPs can form film on various surfaces. Thus, these NPs requires no host layer and can be applied directly to electrode surface when optoelectronic applications e.g. OLEDs or WOLEDs are considered.en_US
dc.description.statementofresponsibilityby Emre Köken.en_US
dc.format.extentxv, 84 pages : illustrations (some color), charts.en_US
dc.language.isoEnglishen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectConjugated oligomersen_US
dc.subjectConjugated oligomer nanoparticlesen_US
dc.subjectFRETen_US
dc.subjectClick reactionen_US
dc.subjectWhite light emissionen_US
dc.titleSynthesis and characterizations of conjugated oligomers and nanoparticles for optoelectronic and biological applicationsen_US
dc.title.alternativeKonjuge oligomerlerin ve nanoparçacıkların optoelektronik ve biyolojik uygulamları için sentezi ve karakterizasyonuen_US
dc.typeThesisen_US
dc.departmentGraduate Program in Materials Science and Nanotechnologyen_US
dc.publisherBilkent Universityen_US
dc.description.degreeM.S.en_US
dc.identifier.itemidB153765
dc.embargo.release2018-08-01


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