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      Boundary element method for optical force calibration in microfluidic dual-beam optical trap

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      Author
      Solmaz, Mehmet E.
      Çetin, Barbaros
      Baranoglu, B.
      Serhatloglu, Murat
      Bıyıklı, Necmi
      Date
      2015
      Source Title
      Proceedings of SPIE
      Print ISSN
      0277-786X
      Publisher
      SPIE
      Volume
      9548
      Language
      English
      Type
      Conference Paper
      Item Usage Stats
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      Abstract
      The potential use of optical forces in microfluidic environment enables highly selective bio-particle manipulation. Manipulation could be accomplished via trapping or pushing a particle due to optical field. Empirical determination of optical force is often needed to ensure efficient operation of manipulation. The external force applied to a trapped particle in a microfluidic channel is a combination of optical and drag forces. The optical force can be found by measuring the particle velocity for a certain laser power level and a multiplicative correction factor is applied for the proximity of the particle to the channel surface. This method is not accurate especially for small microfluidic geometries where the particle size is in Mie regime and is comparable to channel cross section. In this work, we propose to use Boundary Element Method (BEM) to simulate fluid flow within the micro-channel with the presence of the particle to predict drag force. Pushing experiments were performed in a dual-beam optical trap and particlea's position information was extracted. The drag force acting on the particle was then obtained using BEM and other analytical expressions, and was compared to the calculated optical force. BEM was able to predict the behavior of the optical force due to the inclusion of all the channel walls. © 2015 SPIE.
      Keywords
      Microuidics
      Drag
      Flow of fluids
      Laser optics
      Microfluidics
      Micromanipulators
      Particle size
      Sailing vessels
      Velocity control
      Analytical expressions
      Channel cross section
      Microfluidic environment
      Microfluidic geometry
      Microuidics
      Multiplicative corrections
      Optical force
      Opticaltrapping
      Boundary element method
      Permalink
      http://hdl.handle.net/11693/28141
      Published Version (Please cite this version)
      http://dx.doi.org/10.1117/12.2190319
      Collections
      • Department of Mechanical Engineering 254
      • Nanotechnology Research Center (NANOTAM) 1006
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