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dc.contributor.authorAytac Z.en_US
dc.contributor.authorDogan, S.Y.en_US
dc.contributor.authorTekinay, T.en_US
dc.contributor.authorUyar, Tameren_US
dc.date.accessioned2016-02-08T10:46:57Z
dc.date.available2016-02-08T10:46:57Z
dc.date.issued2014en_US
dc.identifier.issn0927-7765
dc.identifier.urihttp://hdl.handle.net/11693/25569
dc.description.abstractAllyl isothiocyanate (AITC) is known as an efficient antibacterial agent but it has a very high volatility. Herein, AITC and AITC/β-cyclodextrin (CD)-inclusion complex (IC) incorporated in polyvinyl alcohol (PVA) nanofibers were produced via electrospinning. SEM images elucidated that incorporation of AITC and AITC/β-CD-IC into polymer matrix did not affect the bead-free fiber morphology of PVA nanofibers. 1H-NMR and headspace GC-MS analyses revealed that very low amount of AITC was remained in PVA/AITC-NF because of the rapid evaporation of AITC during the electrospinning process. Nevertheless, much higher amount of AITC was preserved in the PVA/AITC/β-CD-IC-NF due to the CD inclusion complexation. The sustained release of AITC from nanofibers was evaluated at 30°C, 50°C and 75°C via headspace GC-MS. When compared to PVA/AITC-NF, PVA/AITC/β-CD-IC-NF has shown higher antibacterial activity against Escherichia coli and Staphylococcus aureus due to the presence of higher amount of AITC in this sample which was preserved by CD-IC. © 2014 Elsevier B.V.en_US
dc.language.isoEnglishen_US
dc.source.titleColloids and Surfaces B: Biointerfacesen_US
dc.relation.isversionofhttp://dx.doi.org/10.1016/j.colsurfb.2014.04.006en_US
dc.subjectAllyl isothiocyanateen_US
dc.subjectAntibacterial activityen_US
dc.subjectElectrospinningen_US
dc.subjectNanofibersen_US
dc.subjectReleaseen_US
dc.subjectβ-Cyclodextrinen_US
dc.subjectBacteriaen_US
dc.subjectCyclodextrinsen_US
dc.subjectElectrospinningen_US
dc.subjectEscherichia colien_US
dc.subjectAllyl isothiocyanateen_US
dc.subjectAnti-bacterial activityen_US
dc.subjectCyclodextrin complexesen_US
dc.subjectElectrospinning processen_US
dc.subjectElectrospun nanofibersen_US
dc.subjectInclusion complexationen_US
dc.subjectPoly (vinyl alcohol) (PVA)en_US
dc.subjectReleaseen_US
dc.subjectNanofibersen_US
dc.subjectallyl isothiocyanateen_US
dc.subjectbeta cyclodextrinen_US
dc.subjectnanofiberen_US
dc.subjectpolyvinyl alcoholen_US
dc.subjectallyl isothiocyanateen_US
dc.subjectantiinfective agenten_US
dc.subjectbeta cyclodextrinen_US
dc.subjectbeta cyclodextrin derivativeen_US
dc.subjectisothiocyanic acid derivativeen_US
dc.subjectnanofiberen_US
dc.subjectsolution and solubilityen_US
dc.subjectarticleen_US
dc.subjectbactericidal activityen_US
dc.subjectbacterium colonyen_US
dc.subjectcomplex formationen_US
dc.subjectconcentration (parameters)en_US
dc.subjectcontrolled studyen_US
dc.subjectcrystal structureen_US
dc.subjectelectrospinningen_US
dc.subjectEscherichia colien_US
dc.subjectevaporationen_US
dc.subjectmass fragmentographyen_US
dc.subjectnanoencapsulationen_US
dc.subjectnonhumanen_US
dc.subjectpriority journalen_US
dc.subjectproton nuclear magnetic resonanceen_US
dc.subjectscanning electron microscopyen_US
dc.subjectStaphylococcus aureusen_US
dc.subjecttensile strengthen_US
dc.subjectbacterial counten_US
dc.subjectchemistryen_US
dc.subjectdrug effectsen_US
dc.subjectdrug releaseen_US
dc.subjectgrowth, development and agingen_US
dc.subjectmicrobial sensitivity testen_US
dc.subjectnanotechnologyen_US
dc.subjectproceduresen_US
dc.subjectsolution and solubilityen_US
dc.subjectultrastructureen_US
dc.subjectX ray diffractionen_US
dc.subjectAnti-Bacterial Agentsen_US
dc.subjectbeta-Cyclodextrinsen_US
dc.subjectColony Count, Microbialen_US
dc.subjectDrug Liberationen_US
dc.subjectEscherichia colien_US
dc.subjectIsothiocyanatesen_US
dc.subjectMicrobial Sensitivity Testsen_US
dc.subjectNanofibersen_US
dc.subjectNanotechnologyen_US
dc.subjectProton Magnetic Resonance Spectroscopyen_US
dc.subjectSolutionsen_US
dc.subjectStaphylococcus aureusen_US
dc.subjectX-Ray Diffractionen_US
dc.titleRelease and antibacterial activity of allyl isothiocyanate/β-cyclodextrin complex encapsulated in electrospun nanofibersen_US
dc.typeArticleen_US
dc.citation.spage125en_US
dc.citation.epage131en_US
dc.citation.volumeNumber120en_US
dc.identifier.doi10.1016/j.colsurfb.2014.04.006en_US
dc.publisherElsevieren_US
dc.contributor.bilkentauthorUyar, Tamer
buir.contributor.orcidUyar, Tamer|0000-0002-3989-4481en_US


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