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      Intravascular MR-monitored balloon angioplasty: An in vivo feasibility study

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      Author(s)
      Yang, Xiaoming
      Bolster Jr., B. D.
      Kraitchman, D. L.
      Atalar, Ergin
      Date
      1998
      Source Title
      Journal of Vascular and Interventional Radiology
      Print ISSN
      1051-0443
      Publisher
      Elsevier Inc.
      Volume
      9
      Issue
      6
      Pages
      953 - 959
      Language
      English
      Type
      Article
      Item Usage Stats
      196
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      207
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      Abstract
      PURPOSE: To develop a new method for monitoring balloon angioplasty by using an intravascular magnetic resonance (MR) imaging technique. MATERIALS AND METHODS: Nine New Zealand White rabbits were used: seven for technique refinement, including surgery, device insertion, stenosis creation, and MR protocol development; and two for the final MR imaging of the balloon angioplasty. The in vivo experimental method involved insertion of a catheter antenna and a balloon catheter, via femoral arteriotomies bilaterally, into the target site of the upper abdominal aorta, where a stenosis was artificially created by binding a plastic cable tie. Then, the entire process of the dilation of the stenosis with balloon inflation was monitored under MR fluoroscopy. RESULTS: Catheter insertions were successful, and a 5-mm-long stenosis of the aorta was produced in all nine rabbits. Eight complete balloon angioplasty procedures were satisfactorily monitored and recorded, showing clearly the stenosis of the aorta at the beginning of the procedure, the dilation of the stenosis during the balloon inflation, and the complete opening of the stenosis after balloon dilation. CONCLUSION: Preliminary results of in vivo balloon angioplasty monitored with intravascular MR imaging are presented. MR fluoroscopy, based on the intravascular MR imaging technique, may represent a potential alternative to x-ray fluoroscopy for guiding interventional treatment of cardiovascular diseases.
      Keywords
      Magnetic resonance (MR), intravascular
      Gadodiamide
      Gadolinium pentetate
      Abdominal aorta
      Animal experiment
      Aorta stenosis
      Balloon catheter
      Balloon dilatation
      Contrast enhancement
      Image analysis
      Interventional radiology
      Nuclear magnetic resonance imaging
      Percutaneous transluminal angioplasty
      Fluoroscopy
      Gadolinium DTPA
      Permalink
      http://hdl.handle.net/11693/25306
      Published Version (Please cite this version)
      https://doi.org/10.1016/S1051-0443(98)70429-4
      Collections
      • Department of Electrical and Electronics Engineering 3863
      • National Magnetic Resonance Research Center (UMRAM) 250
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