• About
  • Policies
  • What is open access
  • Library
  • Contact
Advanced search
      View Item 
      •   BUIR Home
      • Scholarly Publications
      • Faculty of Engineering
      • Department of Electrical and Electronics Engineering
      • View Item
      •   BUIR Home
      • Scholarly Publications
      • Faculty of Engineering
      • Department of Electrical and Electronics Engineering
      • View Item
      JavaScript is disabled for your browser. Some features of this site may not work without it.

      Model based analysis of the variation in Korotkoff sound onset time during exercise

      Thumbnail
      View / Download
      258.6 Kb
      Author(s)
      Türkmen, A.
      Ider, Y. Z.
      Date
      2001
      Source Title
      Physiological Measurement
      Print ISSN
      0967-3334
      Publisher
      Institute of Physics Publishing
      Volume
      22
      Issue
      3
      Pages
      433 - 445
      Language
      English
      Type
      Article
      Item Usage Stats
      209
      views
      224
      downloads
      Abstract
      In this study, a minimal mathematical model of the cardiovascular system is used to study the effects of changes in arterial compliance and cardiac contractility on the onset time of Korotkoff sounds during an auscultatory procedure. The model provides blood pressure waveforms in the ventricle, the aorta and the brachial artery. From these waveforms, pre-ejection time, pulse propagation time and rise time of the blood pressure at the brachial artery can be computed. The time delay between onset time of ECG Q wave and onset time of Korotkoff sound is the sum of these three times. Rise time is zero and the time delay is minimal when the cuff pressure is slightly above the diastolic pressure. This minimum time delay is represented by QKD. Simulation results suggest that during the Bruce exercise protocol QKD decreases to one-third of its pre-exercise value if the cardiac contractility increases threefold. The effect of arterial compliance is not as significant as that of the cardiac contractility. From data recorded during an exercise test, it is observed that QKD decreases considerably as the test load is increased. We show in this study that the amount of decrease in QKD can be used as an index of the amount of increase in cardiac contractility during an exercise ECG test. Use of signal averaging for reducing the effect of motion artifacts during an exercise test is also shown to be very instrumental for making accurate QKD measurements.
      Keywords
      Arterial compliance
      Cardiac contractility
      Cardiovascular system modelling
      Diastolic pressure
      Exercise test
      Korotkoff sound
      Pre-ejection time
      Pulse pressure propagation
      QKD
      Systolic pressure
      Aorta
      Artery compliance
      Blood pressure measurement
      Brachial artery
      Cardiovascular system
      Computer simulation
      Electrocardiogram
      Heart auscultation
      Heart muscle contractility
      Heart ventricle
      Heart ventricle ejection time
      Korotkow sound
      Mathematical model
      Q wave
      QKD interval
      Signal averaged electrocardiography
      Aorta
      Auscultation
      Blood Pressure
      Brachial Artery
      Compliance
      Electrocardiography
      Models, Cardiovascular
      Permalink
      http://hdl.handle.net/11693/24809
      Published Version (Please cite this version)
      http://dx.doi.org/10.1088/0967-3334/22/3/302
      Collections
      • Department of Electrical and Electronics Engineering 4011
      Show full item record

      Related items

      Showing items related by title, author, creator and subject.

      • Thumbnail

        Oxygen partial pressure dependence of magnetic, optical and magneto-optical properties of epitaxial cobalt-substituted SrTiO3 films 

        Onbaşli, M.C.; Goto, T.; Tang, A.; Pan, A.; Battal, E.; Okyay, Ali Kemal; Dionne G.F.; Ross, C.A. (OSA - The Optical Society, 2015)
        Cobalt-substituted SrTiO3 films (SrTi0.70Co0.30O3-δ) were grown on SrTiO3 substrates using pulsed laser deposition under oxygen pressures ranging from 1 μTorr to 20 mTorr. The effect of oxygen pressure on structural, ...
      • Thumbnail

        Effect of six weeks aerobic training upon blood trace metals levels 

        Savaş, S.; Şenel, Ö.; Çelikkan, H.; Uǧraş, A.; Aksu, M. L. (2006)
        This study was carried out to investigate the effects of 6-week aerobic exercise program upon blood Zn and Cu levels. There were 12 male university students with an average age of 21.67+/-0.89 years and no regular training ...
      • Thumbnail

        Effect of reactor pressure on optical and electrical properties of InN films grown by high-pressure chemical vapor deposition 

        Alevli, M.; Gungor, N.; Alkis, S.; Ozgit Akgun, C.; Donmez, I.; Okyay, Ali Kemal; Gamage, S.; Senevirathna, I.; Dietz, N.; Bıyıklı, Necmi (Wiley - V C H Verlag GmbH & Co. KGaA, 2015)
        The influences of reactor pressure on the stoichiometry, free carrier concentration, IR and Hall determined mobility, effective optical band edge, and optical phonon modes of HPCVD grown InN films have been analysed and ...

      Browse

      All of BUIRCommunities & CollectionsTitlesAuthorsAdvisorsBy Issue DateKeywordsTypeDepartmentsCoursesThis CollectionTitlesAuthorsAdvisorsBy Issue DateKeywordsTypeDepartmentsCourses

      My Account

      Login

      Statistics

      View Usage StatisticsView Google Analytics Statistics

      Bilkent University

      If you have trouble accessing this page and need to request an alternate format, contact the site administrator. Phone: (312) 290 2976
      © Bilkent University - Library IT

      Contact Us | Send Feedback | Off-Campus Access | Admin | Privacy