• About
  • Policies
  • What is open access
  • Library
  • Contact
Advanced search
      View Item 
      •   BUIR Home
      • Scholarly Publications
      • Faculty of Engineering
      • Department of Computer Engineering
      • View Item
      •   BUIR Home
      • Scholarly Publications
      • Faculty of Engineering
      • Department of Computer Engineering
      • View Item
      JavaScript is disabled for your browser. Some features of this site may not work without it.

      PATIKAmad: putting microarray data into pathway context

      Thumbnail
      View / Download
      255.8 Kb
      Author(s)
      Babur, Özgün
      Colak, Recep
      Demir, Emek
      Doğrusöz, Uğur
      Date
      2008-06
      Source Title
      Proteomics
      Print ISSN
      1615-9853
      Electronic ISSN
      1615-9861
      Publisher
      Wiley - V C H Verlag GmbH & Co. KGaA
      Volume
      8
      Issue
      11
      Pages
      2196 - 2198
      Language
      English
      Type
      Article
      Item Usage Stats
      256
      views
      250
      downloads
      Abstract
      High-throughput experiments, most significantly DNA microarrays, provide us with system-scale profiles. Connecting these data with existing biological networks poses a formidable challenge to uncover facts about a cell's proteome. Studies and tools with this purpose are limited to networks with simple structure, such as protein-protein interaction graphs, or do not go much beyond than simply displaying values on the network. We have built a microarray data analysis tool, named PATIKAmad, which can be used to associate microarray data with the pathway models in mechanistic detail, and provides facilities for visualization, clustering, querying, and navigation of biological graphs related with loaded microarray experiments. PATIKAmad is freely available to noncommercial users as a new module of PATIKAweb at http://web.patika.org. © 2008 Wiley-VCH Verlag GmbH & Co. KGaA.
      Keywords
      Bioinformatics
      Gene expression
      Molecular interaction
      Pathways
      DNA microarray
      Internet
      Microarray analysis
      Priority journal
      Protein database
      Protein protein interaction
      Algorithms
      Cluster analysis
      Computational biology
      Data interpretation
      Gene expression regulation
      MAP kinase signaling system
      Oligonucleotide array sequence analysis
      Pattern recognition
      Protein Interaction Mapping
      Proteomics
      Software
      User-computer interface
      Permalink
      http://hdl.handle.net/11693/23096
      Published Version (Please cite this version)
      http://dx.doi.org/10.1002/pmic.200700769
      Collections
      • Bilkent Center for Bioinformatics (BCBI) 19
      • Department of Computer Engineering 1510
      Show full item record

      Browse

      All of BUIRCommunities & CollectionsTitlesAuthorsAdvisorsBy Issue DateKeywordsTypeDepartmentsCoursesThis CollectionTitlesAuthorsAdvisorsBy Issue DateKeywordsTypeDepartmentsCourses

      My Account

      Login

      Statistics

      View Usage StatisticsView Google Analytics Statistics

      Bilkent University

      If you have trouble accessing this page and need to request an alternate format, contact the site administrator. Phone: (312) 290 2976
      © Bilkent University - Library IT

      Contact Us | Send Feedback | Off-Campus Access | Admin | Privacy